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Takotsubo2014 - Analysis Deformation Dependent Electromechanical Coupling Lab

About lab

Source-faithful physiology lab for Takotsubo modelling, Land et al. 2014. Public controls and outputs are mapped to real source symbols for calcium handling.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packagetakotsubo2014-analysis-deformation-dependent-electromechanical-c
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_crossbridges_xb",
        "label": "Initial Crossbridges Xb",
        "maps_to": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.initial_crossbridges_xb",
        "description": "Initial value for Crossbridges Xb. Maps to source symbol `xb`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "dimensionless"
        ]
      },
      {
        "name": "initial_model_state_q_1",
        "label": "Initial Model State Q 1 (source Q_1)",
        "maps_to": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.initial_model_state_q_1",
        "description": "Initial value for Model State Q 1 (source Q_1). Maps to source symbol `Q_1`. Units: dimensionless. Naming evidence: source symbol is dimensionless but lacks enough evidence for a biological label.",
        "accepted_units": [
          "dimensionless"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.variable_labels"
      },
      {
        "name": "alpha_1",
        "label": "Alpha 1",
        "maps_to": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.alpha_1",
        "description": "Alpha 1. Maps to source symbol `alpha_1`. Units: per_ms. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "alpha_2",
        "label": "Alpha 2",
        "maps_to": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.alpha_2",
        "description": "Alpha 2. Maps to source symbol `alpha_2`. Units: per_ms. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "crossbridges_xb",
        "label": "Crossbridges Xb",
        "maps_to": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.crossbridges_xb",
        "description": "Crossbridges Xb. Maps to source symbol `xb`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "model_state_q_1",
        "label": "Model State Q 1 (source Q_1)",
        "maps_to": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.model_state_q_1",
        "description": "Model State Q 1 (source Q_1). Maps to source symbol `Q_1`. Units: dimensionless. Naming evidence: source symbol is dimensionless but lacks enough evidence for a biological label."
      },
      {
        "name": "model_state_q_2",
        "label": "Model State Q 2 (source Q_2)",
        "maps_to": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.model_state_q_2",
        "description": "Model State Q 2 (source Q_2). Maps to source symbol `Q_2`. Units: dimensionless. Naming evidence: source symbol is dimensionless but lacks enough evidence for a biological label."
      },
      {
        "name": "trpn",
        "label": "Trpn",
        "maps_to": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.trpn",
        "description": "Trpn. Maps to source symbol `TRPN`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      }
    ]
  },
  "title": "Takotsubo2014 - Analysis Deformation Dependent Electromechanical Coupling Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model",
      "alias": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model",
      "parameters": {
        "model_path": "data/Land_et_al_2012_v2.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model_state"
      ],
      "from": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model_summary"
      ],
      "from": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model_trajectory"
      ],
      "from": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model_variable_labels"
      ],
      "from": "physiology_cellml_takotsubo_modelling_land_et_al_2014_1b9_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Takotsubo modelling, Land et al. 2014. Public controls and outputs are mapped to real source symbols for calcium handling.",
  "schema_version": "2.0"
}

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