Abernathy2016 - glioblastoma treatment Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_tumor_burden",
        "label": "Tumor",
        "units": "native SBML value",
        "default": 70,
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.initial_tumor_burden",
        "description": "Initial Tumor. Sets the initial value of bundled SBML symbol `Tumor`."
      },
      {
        "name": "initial_cancer_stem_cells",
        "label": "CancerStemCell",
        "units": "native SBML value",
        "default": 30,
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.initial_cancer_stem_cells",
        "description": "Initial CancerStemCell. Sets the initial value of bundled SBML symbol `CancerStemCell`."
      },
      {
        "name": "initial_cytotoxic_t_cells",
        "label": "CytotoxicTcell",
        "units": "native SBML value",
        "default": 250,
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.initial_cytotoxic_t_cells",
        "description": "Initial CytotoxicTcell. Sets the initial value of bundled SBML symbol `CytotoxicTcell`."
      },
      {
        "name": "initial_tgf_beta",
        "label": "TGFb",
        "units": "native SBML value",
        "default": 50,
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.initial_tgf_beta",
        "description": "Initial TGFb. Sets the initial value of bundled SBML symbol `TGFb`."
      },
      {
        "name": "initial_ifn_gamma",
        "label": "IFNy",
        "units": "native SBML value",
        "default": 50,
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.initial_ifn_gamma",
        "description": "Initial IFNy. Sets the initial value of bundled SBML symbol `IFNy`."
      },
      {
        "name": "initial_mhc_i",
        "label": "MHC1",
        "units": "native SBML value",
        "default": 50,
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.initial_mhc_i",
        "description": "Initial MHC1. Sets the initial value of bundled SBML symbol `MHC1`."
      }
    ],
    "outputs": [
      {
        "name": "tumor_burden",
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.tumor_burden",
        "description": "Tumor observable. Maps to SBML symbol `Tumor`."
      },
      {
        "name": "cancer_stem_cells",
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.cancer_stem_cells",
        "description": "CancerStemCell observable. Maps to SBML symbol `CancerStemCell`."
      },
      {
        "name": "cytotoxic_t_cells",
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.cytotoxic_t_cells",
        "description": "CytotoxicTcell observable. Maps to SBML symbol `CytotoxicTcell`."
      },
      {
        "name": "tgf_beta",
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.tgf_beta",
        "description": "TGFb observable. Maps to SBML symbol `TGFb`."
      },
      {
        "name": "ifn_gamma",
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.ifn_gamma",
        "description": "IFNy observable. Maps to SBML symbol `IFNy`."
      },
      {
        "name": "mhc_i",
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.mhc_i",
        "description": "MHC1 observable. Maps to SBML symbol `MHC1`."
      },
      {
        "name": "state",
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.state",
        "description": "Full raw SBML observable record for reproducibility and downstream visualisation."
      },
      {
        "name": "summary",
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.summary",
        "description": "Change and peak summary across the simulated SBML observables."
      },
      {
        "name": "species_labels",
        "maps_to": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.species_labels",
        "description": "Mapping from selected raw SBML observable symbols to display labels."
      }
    ]
  },
  "tags": [
    "biomodels_ebi",
    "curated",
    "drug-response",
    "faithful",
    "oncology",
    "pharmacology",
    "physiology",
    "sbml",
    "systemsbiology",
    "tumor-growth"
  ],
  "title": "Abernathy2016 - glioblastoma treatment Lab",
  "models": [
    {
      "path": "owned/models/oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model",
      "alias": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model",
      "provenance": {
        "owned_path": "owned/models/oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model_state"
      ],
      "from": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.state"
    },
    {
      "to": [
        "visualisation.oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model_summary"
      ],
      "from": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.summary"
    },
    {
      "to": [
        "visualisation.oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model_species_labels"
      ],
      "from": "oncology_sbml_abernathy2016_glioblastoma_treatment_biomd0000000757_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "The paper describes a model of glioblastoma. Created by COPASI 4.25 (Build 207) This model is described in the article: Modeling the Treatment of Glioblastoma Multiforme and Cancer Stem Cells with Ord.",
  "schema_version": "2.0"
}