Dwivedi2014 - Crohns IL6 Disease model - Anti-IL6R Antibody Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_interleukin_6",
        "label": "Initial Interleukin 6",
        "units": "native source value",
        "default": 0.000435628896551166,
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.initial_interleukin_6",
        "description": "Initial Interleukin 6. Sets the initial value of bundled SBML species `mwf626e95e_543f_41e4_aad4_c6bf60ab345b`."
      },
      {
        "name": "initial_unresolved_immune_observable_1",
        "label": "Initial Unresolved Immune Observable 1",
        "units": "native source value",
        "default": 3.9,
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.initial_unresolved_immune_observable_1",
        "description": "Initial Unresolved Immune Observable 1. Sets the initial value of bundled SBML species `mwbbbce920_e8dd_4320_9386_fc94bfb2fc99`."
      },
      {
        "name": "initial_soluble_interleukin_6_sgp130_complex",
        "label": "Initial Soluble Interleukin 6 Sgp130 Complex",
        "units": "native source value",
        "default": 0.0874060669217432,
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.initial_soluble_interleukin_6_sgp130_complex",
        "description": "Initial Soluble Interleukin 6 Sgp130 Complex. Sets the initial value of bundled SBML species `mw810ff751_fa4e_4143_bd50_169b3e325e1e`."
      },
      {
        "name": "initial_reactive_protein",
        "label": "Initial Reactive Protein",
        "units": "native source value",
        "default": 221.06367608557,
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.initial_reactive_protein",
        "description": "Initial Reactive Protein. Sets the initial value of bundled SBML species `mw114aa90f_5f5b_4fe8_9406_361c8489b6a1`."
      },
      {
        "name": "initial_unresolved_immune_observable_2",
        "label": "Initial Unresolved Immune Observable 2",
        "units": "native source value",
        "default": 4.25350679194445,
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.initial_unresolved_immune_observable_2",
        "description": "Initial Unresolved Immune Observable 2. Sets the initial value of bundled SBML species `mw30ae63db_6cd3_4b6f_93ad_3350cd360bcc`."
      },
      {
        "name": "dose",
        "label": "Dose",
        "units": "native source value",
        "default": 300,
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.dose",
        "description": "Dose. Sets bundled SBML parameter `Dose`."
      },
      {
        "name": "dose_q2w_parameter",
        "label": "Dose Q2w Parameter",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.dose_q2w_parameter",
        "description": "Dose Q2w Parameter. Sets bundled SBML parameter `parameter_1`."
      },
      {
        "name": "dose_q2w_initial_parameter",
        "label": "Dose Q2w Initial Parameter",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.dose_q2w_initial_parameter",
        "description": "Dose Q2w Initial Parameter. Sets bundled SBML parameter `ModelValue_99`."
      },
      {
        "name": "dose_initial_parameter",
        "label": "Dose Initial Parameter",
        "units": "native source value",
        "default": 300,
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.dose_initial_parameter",
        "description": "Dose Initial Parameter. Sets bundled SBML parameter `ModelValue_98`."
      }
    ],
    "outputs": [
      {
        "name": "interleukin_6",
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.interleukin_6"
      },
      {
        "name": "unresolved_immune_observable_1",
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.unresolved_immune_observable_1"
      },
      {
        "name": "soluble_interleukin_6_sgp130_complex",
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.soluble_interleukin_6_sgp130_complex"
      },
      {
        "name": "reactive_protein",
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.reactive_protein"
      },
      {
        "name": "unresolved_immune_observable_2",
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.unresolved_immune_observable_2"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.species_labels"
      }
    ]
  },
  "title": "Dwivedi2014 - Crohns IL6 Disease model - Anti-IL6R Antibody Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model",
      "alias": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model_state"
      ],
      "from": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model_summary"
      ],
      "from": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model_species_labels"
      ],
      "from": "immunology_sbml_dwivedi2014_crohns_il6_disease_model_anti_il6r_a_biomd0000000537_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "Dwivedi2014 - Crohns IL6 Disease model -Anti-IL6R Antibody This model is comprised of four models: [BIOMD0000000534] Healthy Volunteer model [BIOMD0000000535] Crohn's Disease - IL-6 Antibody [BIOMD000. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}