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Mahajan2008 - Rabbit Ventricular Action Potential Replicating Cardiac Lab

About lab

Source-faithful physiology lab for Mahajan, Shiferaw, Sato, Baher, Olcese, Xie, Yang, Chen, Restrepo, Karma, Garfinkel, Qu, Weiss, 2008. Public controls and outputs are mapped to real source symbols for electrophysiology.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packagemahajan2008-rabbit-ventricular-action-potential-replicating-card
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_intracellular_calcium",
        "label": "Initial Intracellular Calcium",
        "maps_to": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.initial_intracellular_calcium",
        "description": "Initial value for Intracellular Calcium. Maps to source symbol `Ca_i`. Units: uM. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "uM"
        ]
      },
      {
        "name": "initial_intracellular_sodium",
        "label": "Initial Intracellular Sodium",
        "maps_to": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.initial_intracellular_sodium",
        "description": "Initial value for Intracellular Sodium. Maps to source symbol `Na_i`. Units: mM. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "mM"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.variable_labels"
      },
      {
        "name": "intracellular_calcium",
        "label": "Intracellular Calcium",
        "maps_to": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.intracellular_calcium",
        "description": "Intracellular Calcium. Maps to source symbol `Ca_i`. Units: uM. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "intracellular_sodium",
        "label": "Intracellular Sodium",
        "maps_to": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.intracellular_sodium",
        "description": "Intracellular Sodium. Maps to source symbol `Na_i`. Units: mM. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "extracellular_calcium",
        "label": "Extracellular Calcium",
        "maps_to": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.extracellular_calcium",
        "description": "Extracellular Calcium. Maps to source symbol `Ca_o`. Units: mM. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "extracellular_sodium",
        "label": "Extracellular Sodium",
        "maps_to": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.extracellular_sodium",
        "description": "Extracellular Sodium. Maps to source symbol `Na_o`. Units: mM. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "extracellular_potassium",
        "label": "Extracellular Potassium",
        "maps_to": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.extracellular_potassium",
        "description": "Extracellular Potassium. Maps to source symbol `K_o`. Units: mM. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "intracellular_potassium",
        "label": "Intracellular Potassium",
        "maps_to": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.intracellular_potassium",
        "description": "Intracellular Potassium. Maps to source symbol `K_i`. Units: mM. Naming evidence: source symbol, component, or units provide a direct public name."
      }
    ]
  },
  "title": "Mahajan2008 - Rabbit Ventricular Action Potential Replicating Cardiac Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model",
      "alias": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model",
      "parameters": {
        "model_path": "data/mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_restrepo_karma_garfinkel_qu_weiss_2008.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model_state"
      ],
      "from": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model_summary"
      ],
      "from": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model_trajectory"
      ],
      "from": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model_variable_labels"
      ],
      "from": "physiology_cellml_mahajan_shiferaw_sato_baher_olcese_xie_yang_chen_mahajanshiferawsatobaherolcesexieyangchenrestrepokarmagarfinkelquweiss2008_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Mahajan, Shiferaw, Sato, Baher, Olcese, Xie, Yang, Chen, Restrepo, Karma, Garfinkel, Qu, Weiss, 2008. Public controls and outputs are mapped to real source symbols for electrophysiology.",
  "schema_version": "2.0"
}

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