Goldbeter2008 - Modeling Segmentation Clock Network Coupled Oscillations Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_active_erk",
        "label": "Initial Active Erk",
        "maps_to": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.initial_active_erk",
        "description": "Initial value for Active Erk. Maps to source symbol `ERKa`. Units: nanomolar. Naming evidence: source metadata names `ERKa` as `active ERK`.",
        "accepted_units": [
          "nanomolar"
        ]
      },
      {
        "name": "initial_active_ras",
        "label": "Initial Active Ras",
        "maps_to": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.initial_active_ras",
        "description": "Initial value for Active Ras. Maps to source symbol `Rasa`. Units: nanomolar. Naming evidence: source metadata names `Rasa` as `active Ras`.",
        "accepted_units": [
          "nanomolar"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.variable_labels"
      },
      {
        "name": "axin2_protein",
        "label": "Axin2 Protein",
        "maps_to": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.axin2_protein",
        "description": "Axin2 Protein. Maps to source symbol `A`. Units: nanomolar. Naming evidence: source metadata names `A` as `Axin2 protein`."
      },
      {
        "name": "free_kinase_gsk3",
        "label": "Free Kinase Gsk3",
        "maps_to": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.free_kinase_gsk3",
        "description": "Free Kinase Gsk3. Maps to source symbol `K`. Units: nanomolar. Naming evidence: source metadata names `K` as `free kinase Gsk3`."
      },
      {
        "name": "lunatic_fringe_protein",
        "label": "Lunatic Fringe Protein",
        "maps_to": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.lunatic_fringe_protein",
        "description": "Lunatic Fringe Protein. Maps to source symbol `F`. Units: nanomolar. Naming evidence: source metadata names `F` as `Lunatic fringe protein`."
      },
      {
        "name": "nuclear_beta_catenin",
        "label": "Nuclear Beta Catenin",
        "maps_to": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.nuclear_beta_catenin",
        "description": "Nuclear Beta Catenin. Maps to source symbol `BN`. Units: nanomolar. Naming evidence: source metadata names `BN` as `nuclear beta-catenin`."
      },
      {
        "name": "phosphorylated_beta_catenin",
        "label": "Phosphorylated Beta Catenin",
        "maps_to": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.phosphorylated_beta_catenin",
        "description": "Phosphorylated Beta Catenin. Maps to source symbol `Bp`. Units: nanomolar. Naming evidence: source metadata names `Bp` as `phosphorylated beta-catenin`."
      },
      {
        "name": "non_phosphorylated_beta_catenin",
        "label": "Non Phosphorylated Beta Catenin",
        "maps_to": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.non_phosphorylated_beta_catenin",
        "description": "Non Phosphorylated Beta Catenin. Maps to source symbol `B`. Units: nanomolar. Naming evidence: source metadata names `B` as `non-phosphorylated beta-catenin`."
      }
    ]
  },
  "title": "Goldbeter2008 - Modeling Segmentation Clock Network Coupled Oscillations Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model",
      "alias": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model",
      "parameters": {
        "model_path": "data/goldbeter_pourquie_2008_a.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model_state"
      ],
      "from": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model_summary"
      ],
      "from": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model_trajectory"
      ],
      "from": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model_variable_labels"
      ],
      "from": "physiology_cellml_goldbeter_pourquie_2008_goldbeterpourquie2008_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Goldbeter, Pourquie, 2008. Public controls and outputs are mapped to real source symbols for oscillatory physiology.",
  "schema_version": "2.0"
}