About lab
BioSystems (2007), doi:10.1016/j.biosystems.2008.06.007 In-silico study of kinetochore control, amplification, and inhibition effects in MCC assembly Bashar Ibrahim, Eberhard Schmitt, Peter Dittrich,. It can be used to explore systemsbiology ibrahim2008 mcc assembly kdm BioModels0000000193 dynamics and compare simulation behavior across conditions.
Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packageibrahim2008-mcc-assembly-model-kdm-lab
Created2026-05-17
Updated2026-05-17
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation
Manifest
{
"io": {
"inputs": [
{
"name": "initial_o_mad2",
"label": "Initial O Mad2",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.initial_o_mad2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `OMad2`."
},
{
"name": "initial_bub3_bub_r1",
"label": "Initial Bub3 Bub R1",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.initial_bub3_bub_r1",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Bub3_BubR1`."
},
{
"name": "initial_mad1_c_mad2",
"label": "Initial Mad1 C Mad2",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.initial_mad1_c_mad2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Mad1_CMad2`."
},
{
"name": "initial_mad1_c_mad2_o_mad2",
"label": "Initial Mad1 C Mad2 O Mad2",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.initial_mad1_c_mad2_o_mad2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Mad1_CMad2_OMad2`."
},
{
"name": "initial_cdc20_c_mad2",
"label": "Initial Cdc20 C Mad2",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.initial_cdc20_c_mad2",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Cdc20_CMad2`."
},
{
"name": "initial_bub3_bub_r1_cdc20",
"label": "Initial Bub3 Bub R1 Cdc20",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.initial_bub3_bub_r1_cdc20",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Bub3_BubR1_Cdc20`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.state"
},
{
"name": "summary",
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},
{
"name": "species_labels",
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},
{
"name": "o_mad2",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.o_mad2"
},
{
"name": "bub3_bub_r1",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.bub3_bub_r1"
},
{
"name": "mad1_c_mad2",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.mad1_c_mad2"
},
{
"name": "mad1_c_mad2_o_mad2",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.mad1_c_mad2_o_mad2"
},
{
"name": "cdc20_c_mad2",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.cdc20_c_mad2"
},
{
"name": "bub3_bub_r1_cdc20",
"maps_to": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.bub3_bub_r1_cdc20"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Ibrahim2008 Mcc Assembly Model Kdm Lab",
"models": [
{
"path": "owned/models/systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model",
"alias": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model",
"provenance": {
"owned_path": "owned/models/systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model"
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},
{
"path": "owned/models/visualisation",
"alias": "visualisation",
"provenance": {
"owned_path": "owned/models/visualisation"
}
}
],
"wiring": [
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{
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"from": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.summary"
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{
"to": [
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"from": "systemsbiology_sbml_ibrahim2008_mcc_assembly_model_kdm_biomd0000000193_model.species_labels"
}
],
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"description": "BioSystems (2007), doi:10.1016/j.biosystems.2008.06.007 In-silico study of kinetochore control, amplification, and inhibition effects in MCC assembly Bashar Ibrahim, Eberhard Schmitt, Peter Dittrich,. It can be used to explore systemsbiology ibrahim2008 mcc assembly kdm BioModels0000000193 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
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