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Martinez Guimera2017 Generic Negative Feedback Circuit Lab

About lab

Martinez-Guimera2017 - Generic negative feedback circuit (Model 4) This model is described in the article: 'Molecular habituation' as a potential mechanism of gradual homeostatic loss with age. It can be used to explore systemsbiology martinez guimera2017 generic negative feedback dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packagemartinez-guimera2017-generic-negative-feedback-circuit-lab
Created2026-05-17
Updated2026-05-17
generegulationsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
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        "label": "Initial Model State Nil",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.initial_model_state_nil",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Nil`."
      },
      {
        "name": "initial_model_state_s",
        "label": "Initial Model State S",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.initial_model_state_s",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `S`."
      },
      {
        "name": "initial_model_state_o",
        "label": "Initial Model State O",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.initial_model_state_o",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `O`."
      },
      {
        "name": "initial_model_state_n",
        "label": "Initial Model State N",
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        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `N`."
      },
      {
        "name": "initial_model_state_f",
        "label": "Initial Model State F",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.initial_model_state_f",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `F`."
      },
      {
        "name": "initial_model_state_a",
        "label": "Initial Model State A",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.initial_model_state_a",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `A`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.species_labels"
      },
      {
        "name": "nil",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.nil"
      },
      {
        "name": "model_state_s",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.model_state_s"
      },
      {
        "name": "model_state_o",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.model_state_o"
      },
      {
        "name": "model_state_n",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.model_state_n"
      },
      {
        "name": "model_state_f",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.model_state_f"
      },
      {
        "name": "model_state_a",
        "maps_to": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.model_state_a"
      }
    ]
  },
  "tags": [
    "generegulation",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Martinez Guimera2017 Generic Negative Feedback Circuit Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model",
      "alias": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model_state"
      ],
      "from": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model_summary"
      ],
      "from": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model_species_labels"
      ],
      "from": "systemsbiology_sbml_martinez_guimera2017_generic_negative_feedback_c_model1710260003_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Martinez-Guimera2017 - Generic negative feedback circuit (Model 4) This model is described in the article: 'Molecular habituation' as a potential mechanism of gradual homeostatic loss with age. It can be used to explore systemsbiology martinez guimera2017 generic negative feedback dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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