Yamada2003 JAK STAT SOCS1 knockout Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_interferon_receptor_jak_complex",
        "label": "Initial Interferon Receptor JAK Complex",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.initial_interferon_receptor_jak_complex",
        "description": "Initial Interferon Receptor JAK Complex. Sets the initial value of bundled SBML species `IFNRJ`."
      },
      {
        "name": "initial_receptor_jak_complex",
        "label": "Initial Receptor JAK Complex",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.initial_receptor_jak_complex",
        "description": "Initial Receptor JAK Complex. Sets the initial value of bundled SBML species `RJ`."
      },
      {
        "name": "initial_ifnrj_dimer",
        "label": "Initial Ifnrj Dimer",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.initial_ifnrj_dimer",
        "description": "Initial Ifnrj Dimer. Sets the initial value of bundled SBML species `IFNRJ2`."
      },
      {
        "name": "initial_activated_ifnrj_complex",
        "label": "Initial Activated Ifnrj Complex",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.initial_activated_ifnrj_complex",
        "description": "Initial Activated Ifnrj Complex. Sets the initial value of bundled SBML species `IFNRJ2_star`."
      },
      {
        "name": "initial_interferon_receptor_jak2_stat1_complex",
        "label": "Initial Interferon Receptor Jak2 Stat1 Complex",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.initial_interferon_receptor_jak2_stat1_complex",
        "description": "Initial Interferon Receptor Jak2 Stat1 Complex. Sets the initial value of bundled SBML species `IFNRJ2_star_STAT1c`."
      }
    ],
    "outputs": [
      {
        "name": "interferon_receptor_jak_complex",
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.interferon_receptor_jak_complex"
      },
      {
        "name": "receptor_jak_complex",
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.receptor_jak_complex"
      },
      {
        "name": "ifnrj_dimer",
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.ifnrj_dimer"
      },
      {
        "name": "activated_ifnrj_complex",
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.activated_ifnrj_complex"
      },
      {
        "name": "interferon_receptor_jak2_stat1_complex",
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.interferon_receptor_jak2_stat1_complex"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.species_labels"
      }
    ]
  },
  "title": "Yamada2003 JAK STAT SOCS1 knockout Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model",
      "alias": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model_state"
      ],
      "from": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model_summary"
      ],
      "from": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model_species_labels"
      ],
      "from": "immunology_sbml_yamada2003_jak_stat_socs1_knockout_biomd0000000094_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "NCBS Curation Comments: This model shows the control mechanism of Jak-Stat pathway, here SOCS1 (Suppressor of cytokine signaling-I) was identified as the negative regulator of Jak and STAT signal tran. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}