Talemi2015 - Persistent telomere-associated DNA damage foci (TAF), a measure to predict cancer risks Lab

{
  "io": {
    "inputs": [
      {
        "name": "dnadamagefoci_0_source_parameter",
        "label": "DNAdamagefoci 0 source parameter",
        "units": "native SBML value",
        "default": 750.500039901129,
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.dnadamagefoci_0_source_parameter",
        "description": "DNAdamagefoci 0 source parameter. Maps to bundled SBML parameter `DNAdamagefoci_0`."
      },
      {
        "name": "base_dnadamage_source_parameter",
        "label": "BaseDNAdamage source parameter",
        "units": "native SBML value",
        "default": 0.989191113985894,
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.base_dnadamage_source_parameter",
        "description": "BaseDNAdamage source parameter. Maps to bundled SBML parameter `BaseDNAdamage`."
      },
      {
        "name": "initial_fast",
        "label": "FAST",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.initial_fast",
        "description": "Initial FAST. Sets the initial value of bundled SBML symbol `FAST`."
      },
      {
        "name": "initial_slow",
        "label": "SLOW",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.initial_slow",
        "description": "Initial SLOW. Sets the initial value of bundled SBML symbol `SLOW`."
      },
      {
        "name": "initial_fasti",
        "label": "FASTi",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.initial_fasti",
        "description": "Initial FASTi. Sets the initial value of bundled SBML symbol `FASTi`."
      },
      {
        "name": "initial_slowi",
        "label": "SLOWi",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.initial_slowi",
        "description": "Initial SLOWi. Sets the initial value of bundled SBML symbol `SLOWi`."
      }
    ],
    "outputs": [
      {
        "name": "rp",
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.rp",
        "description": "RP observable. Maps to SBML symbol `RP`."
      },
      {
        "name": "fast",
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.fast",
        "description": "FAST observable. Maps to SBML symbol `FAST`."
      },
      {
        "name": "slow",
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.slow",
        "description": "SLOW observable. Maps to SBML symbol `SLOW`."
      },
      {
        "name": "fasti",
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.fasti",
        "description": "FASTi observable. Maps to SBML symbol `FASTi`."
      },
      {
        "name": "slowi",
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.slowi",
        "description": "SLOWi observable. Maps to SBML symbol `SLOWi`."
      },
      {
        "name": "state",
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.state",
        "description": "Full raw SBML observable record for reproducibility and downstream visualisation."
      },
      {
        "name": "summary",
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.summary",
        "description": "Change and peak summary across the simulated SBML observables."
      },
      {
        "name": "species_labels",
        "maps_to": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.species_labels",
        "description": "Mapping from selected raw SBML observable symbols to display labels."
      }
    ]
  },
  "tags": [
    "biomodels_ebi",
    "cellcycle",
    "curated",
    "dna-damage",
    "drug-response",
    "faithful",
    "oncology",
    "pharmacology",
    "physiology",
    "sbml",
    "systemsbiology",
    "tumor-growth"
  ],
  "title": "Talemi2015 - Persistent telomere-associated DNA damage foci (TAF), a measure to predict cancer risks Lab",
  "models": [
    {
      "path": "owned/models/oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model",
      "alias": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model",
      "provenance": {
        "owned_path": "owned/models/oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model_state"
      ],
      "from": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.state"
    },
    {
      "to": [
        "visualisation.oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model_summary"
      ],
      "from": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.summary"
    },
    {
      "to": [
        "visualisation.oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model_species_labels"
      ],
      "from": "oncology_sbml_talemi2015_persistent_telomere_associated_dna_da_model1412200000_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "A Robust Model of DNA Damage Dynamics.Rasgou Talemi and Schaber, 12.20.2014. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.",
  "schema_version": "2.0"
}