About lab
Eftimie2017/2 - interaction of Th and macrophage in melanoma Lab
Curated immunology lab using the bundled source model as the scientific source of truth.
What You'll See
This captured run documents the default Eftimie2017/2 - interaction of Th and macrophage in melanoma configuration for 10.0 time units with a 1.0 communication step. Default inputs include Initial Unresolved Tumor Observable 1, Initial Unresolved Tumor Observable 2, Initial Unresolved Tumor Observable 3, and Initial Unresolved Tumor Observable 4. Reported outputs include unresolved_tumor_observable_1, unresolved_tumor_observable_2, unresolved_tumor_observable_3, and unresolved_tumor_observable_4. The screenshots below pair the run-interpretation table with Tumor-immune burden and Largest state excursions so the README shows both trajectories and the strongest state changes from the same dark-mode run.
Output Visualizations
The run-interpretation table summarizes the configured Eftimie2017/2 - interaction of Th and macrophage in melanoma simulation and its final-state diagnostics.
The Tumor-immune burden time series follows the selected immune, pathogen, tumor, or signaling quantities across the simulated horizon.
The largest state excursions chart ranks the state variables that moved furthest during the run.
The paper describes a model of interaction of Th cells and macrophage in melanoma. Created by COPASI 4.25 (Build 207) This model is described in the article: Modelling and investigation of the CD4 T c.
Runtime
Runs
Metadata
Manifest
{
"io": {
"inputs": [
{
"name": "initial_unresolved_tumor_observable_1",
"label": "Initial Unresolved Tumor Observable 1",
"units": "substance",
"default": 100000,
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.initial_unresolved_tumor_observable_1",
"description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `T`."
},
{
"name": "initial_unresolved_tumor_observable_2",
"label": "Initial Unresolved Tumor Observable 2",
"units": "substance",
"default": 0,
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.initial_unresolved_tumor_observable_2",
"description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `H1`."
},
{
"name": "initial_unresolved_tumor_observable_3",
"label": "Initial Unresolved Tumor Observable 3",
"units": "substance",
"default": 0,
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.initial_unresolved_tumor_observable_3",
"description": "Initial Unresolved Tumor Observable 3. Sets the initial value of bundled SBML species `H2`."
},
{
"name": "initial_unresolved_tumor_observable_4",
"label": "Initial Unresolved Tumor Observable 4",
"units": "substance",
"default": 100,
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.initial_unresolved_tumor_observable_4",
"description": "Initial Unresolved Tumor Observable 4. Sets the initial value of bundled SBML species `M1`."
},
{
"name": "initial_unresolved_tumor_observable_5",
"label": "Initial Unresolved Tumor Observable 5",
"units": "substance",
"default": 0,
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.initial_unresolved_tumor_observable_5",
"description": "Initial Unresolved Tumor Observable 5. Sets the initial value of bundled SBML species `M2`."
}
],
"outputs": [
{
"name": "unresolved_tumor_observable_1",
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.unresolved_tumor_observable_1"
},
{
"name": "unresolved_tumor_observable_2",
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.unresolved_tumor_observable_2"
},
{
"name": "unresolved_tumor_observable_3",
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.unresolved_tumor_observable_3"
},
{
"name": "unresolved_tumor_observable_4",
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.unresolved_tumor_observable_4"
},
{
"name": "unresolved_tumor_observable_5",
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.unresolved_tumor_observable_5"
},
{
"name": "state",
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.state"
},
{
"name": "summary",
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.summary"
},
{
"name": "species_labels",
"maps_to": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.species_labels"
}
]
},
"title": "Eftimie2017/2 - interaction of Th and macrophage in melanoma Lab",
"models": [
{
"path": "owned/models/immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model",
"alias": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model",
"provenance": {
"owned_path": "owned/models/immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model"
}
},
{
"path": "owned/models/visualisation",
"alias": "visualisation",
"provenance": {
"owned_path": "owned/models/visualisation"
}
}
],
"wiring": [
{
"to": [
"visualisation.immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model_state"
],
"from": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.state"
},
{
"to": [
"visualisation.immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model_summary"
],
"from": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.summary"
},
{
"to": [
"visualisation.immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model_species_labels"
],
"from": "immunology_sbml_eftimie2017_2_interaction_of_th_and_macrophage_i_biomd0000000769_model.species_labels"
}
],
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"description": "The paper describes a model of interaction of Th cells and macrophage in melanoma. Created by COPASI 4.25 (Build 207) This model is described in the article: Modelling and investigation of the CD4 T c.",
"schema_version": "2.0"
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