Fassoni2019 - Oncogenesis encompassing mutations and genetic instability Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_normalized_normal_cell_n",
        "label": "Normalized normal cell n",
        "units": "native SBML value",
        "default": 0.99999999,
        "maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.initial_normalized_normal_cell_n",
        "description": "Initial Normalized normal cell n. Sets the initial value of bundled SBML symbol `normalized_normal_cell_n`."
      },
      {
        "name": "initial_normalized_pre_cancer_cell_g",
        "label": "Normalized pre cancer cell g",
        "units": "native SBML value",
        "default": "1e-8",
        "maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.initial_normalized_pre_cancer_cell_g",
        "description": "Initial Normalized pre cancer cell g. Sets the initial value of bundled SBML symbol `normalized_pre_cancer_cell_g`."
      },
      {
        "name": "initial_normalized_cancer_cell_a",
        "label": "Normalized cancer cell a",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.initial_normalized_cancer_cell_a",
        "description": "Initial Normalized cancer cell a. Sets the initial value of bundled SBML symbol `normalized_cancer_cell_a`."
      }
    ],
    "outputs": [
      {
        "name": "normalized_normal_cell_n",
        "maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.normalized_normal_cell_n",
        "description": "Normalized normal cell n observable. Maps to SBML symbol `normalized_normal_cell_n`."
      },
      {
        "name": "normalized_pre_cancer_cell_g",
        "maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.normalized_pre_cancer_cell_g",
        "description": "Normalized pre cancer cell g observable. Maps to SBML symbol `normalized_pre_cancer_cell_g`."
      },
      {
        "name": "normalized_cancer_cell_a",
        "maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.normalized_cancer_cell_a",
        "description": "Normalized cancer cell a observable. Maps to SBML symbol `normalized_cancer_cell_a`."
      },
      {
        "name": "state",
        "maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.state",
        "description": "Full raw SBML observable record for reproducibility and downstream visualisation."
      },
      {
        "name": "summary",
        "maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.summary",
        "description": "Change and peak summary across the simulated SBML observables."
      },
      {
        "name": "species_labels",
        "maps_to": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.species_labels",
        "description": "Mapping from selected raw SBML observable symbols to display labels."
      }
    ]
  },
  "tags": [
    "biomodels_ebi",
    "curated",
    "drug-response",
    "faithful",
    "oncology",
    "pharmacology",
    "physiology",
    "sbml",
    "systemsbiology",
    "tumor-growth"
  ],
  "title": "Fassoni2019 - Oncogenesis encompassing mutations and genetic instability Lab",
  "models": [
    {
      "path": "owned/models/oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model",
      "alias": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model",
      "provenance": {
        "owned_path": "owned/models/oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model_state"
      ],
      "from": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.state"
    },
    {
      "to": [
        "visualisation.oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model_summary"
      ],
      "from": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.summary"
    },
    {
      "to": [
        "visualisation.oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model_species_labels"
      ],
      "from": "oncology_sbml_fassoni2019_oncogenesis_encompassing_mutations_a_biomd0000000807_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This model describes the multistep process that transform a normal cell and its descendants into a malignant tumour by considering three populations: normal, premalignant and cancer cells. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.",
  "schema_version": "2.0"
}