About lab
Al-Tuwairqi2020 - Dynamics of cancer radiovirotherapy - Phase II treatment
This Biosimulant lab wraps Al-Tuwairqi2020 - Dynamics of cancer radiovirotherapy - Phase II treatment as a runnable oncology model with a companion visualization module.
This ordinary differential equation model of cancer radiovirotherapy dynamics is described in the publication:Salma M. It can be used to explore treatment-response dynamics and compare scenario outcomes across configurations.
What You'll See
The lab asks: Does the radiotherapy-linked model show tumour response under baseline source conditions? It runs for 10.0 time units with a communication step of 1.0. The run uses the model defaults declared by the curated SBML wrapper. The generated visualizations focus on Damaged cancer cells, Uninfected cancer cells, Free virus, and Infected cancer cells, combining trajectory, endpoint-comparison, and summary-table views from one completed dark-mode run.
In this captured run, uninfected_cancer_cells carried the largest peak and uninfected_cancer_cells moved by 0.2863 native units across 10.0 simulation windows.
Output Visualizations
Summary table for Al-Tuwairqi2020 - Dynamics of cancer radiovirotherapy - Phase II treatment, reporting the scientific question, observed answer (largest change: uninfected_cancer_cells at 0.2863 native units), evidence (peak observable: uninfected_cancer_cells), dominant module, and caveat.
Trajectories of Damaged cancer cells, Uninfected cancer cells, Free virus, and Infected cancer cells across the 10.0 simulation. In this run Free virus climbed from 0.1000 to 0.1690 and Uninfected cancer cells fell from 0.4000 to 0.1137 — the largest movements among the focused observables.
Endpoint ranking of the focused observables. Top 3 by final value: Free virus = 0.1690, Uninfected cancer cells = 0.1137, Infected cancer cells = 0.0229, with 1 more observable below.
Model Context
- Core model:
models/core - Visualization model:
models/visualisation - Standard:
other - Upstream source:
biomodels_ebi:BIOMD0000001032 - License:
CC0 - Visual scope: Radiotherapy-linked tumour response
- Caveat: Values are native SBML quantities; the cleanup does not reinterpret source equations.
Inputs
| Input | Maps To | Default | Notes |
|---|---|---|---|
| Damaged cancer cells | oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.initial_damaged_cancer_cells | 0.0 | Initial Damaged cancer cells. Sets the initial value of bundled SBML symbol damaged_cancer_cells. |
| Uninfected cancer cells | oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.initial_uninfected_cancer_cells | 0.4 | Initial Uninfected cancer cells. Sets the initial value of bundled SBML symbol uninfected_cancer_cells. |
| Free virus | oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.initial_free_virus | 0.1 | Initial Free virus. Sets the initial value of bundled SBML symbol free_virus. |
| Infected cancer cells | oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.initial_infected_cancer_cells | 0.0 | Initial Infected cancer cells. Sets the initial value of bundled SBML symbol infected_cancer_cells. |
Outputs
| Output | Maps To | Role |
|---|---|---|
damaged_cancer_cells | oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.damaged_cancer_cells | Damaged cancer cells observable. |
uninfected_cancer_cells | oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.uninfected_cancer_cells | Uninfected cancer cells observable. |
free_virus | oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.free_virus | Free virus observable. |
infected_cancer_cells | oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.infected_cancer_cells | Infected cancer cells observable. |
state | oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.state | Full raw SBML observable record for reproducibility and downstream visualisation. |
summary | oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.summary | Change and peak summary across the simulated SBML observables. |
species_labels | oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.species_labels | Mapping from selected raw SBML observable symbols to display labels. |
Runtime
- Duration:
10.0 - Communication step:
1.0
Running Locally
biosimulant labs serve .
This ordinary differential equation model of cancer radiovirotherapy dynamics is described in the publication:Salma M. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.
Runtime
Runs
Metadata
Manifest
{
"io": {
"inputs": [
{
"name": "initial_damaged_cancer_cells",
"label": "Damaged cancer cells",
"units": "native SBML value",
"default": 0,
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.initial_damaged_cancer_cells",
"description": "Initial Damaged cancer cells. Sets the initial value of bundled SBML symbol `damaged_cancer_cells`."
},
{
"name": "initial_uninfected_cancer_cells",
"label": "Uninfected cancer cells",
"units": "native SBML value",
"default": 0.4,
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.initial_uninfected_cancer_cells",
"description": "Initial Uninfected cancer cells. Sets the initial value of bundled SBML symbol `uninfected_cancer_cells`."
},
{
"name": "initial_free_virus",
"label": "Free virus",
"units": "native SBML value",
"default": 0.1,
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.initial_free_virus",
"description": "Initial Free virus. Sets the initial value of bundled SBML symbol `free_virus`."
},
{
"name": "initial_infected_cancer_cells",
"label": "Infected cancer cells",
"units": "native SBML value",
"default": 0,
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.initial_infected_cancer_cells",
"description": "Initial Infected cancer cells. Sets the initial value of bundled SBML symbol `infected_cancer_cells`."
}
],
"outputs": [
{
"name": "damaged_cancer_cells",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.damaged_cancer_cells",
"description": "Damaged cancer cells observable. Maps to SBML symbol `damaged_cancer_cells`."
},
{
"name": "uninfected_cancer_cells",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.uninfected_cancer_cells",
"description": "Uninfected cancer cells observable. Maps to SBML symbol `uninfected_cancer_cells`."
},
{
"name": "free_virus",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.free_virus",
"description": "Free virus observable. Maps to SBML symbol `free_virus`."
},
{
"name": "infected_cancer_cells",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.infected_cancer_cells",
"description": "Infected cancer cells observable. Maps to SBML symbol `infected_cancer_cells`."
},
{
"name": "state",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.state",
"description": "Full raw SBML observable record for reproducibility and downstream visualisation."
},
{
"name": "summary",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.summary",
"description": "Change and peak summary across the simulated SBML observables."
},
{
"name": "species_labels",
"maps_to": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.species_labels",
"description": "Mapping from selected raw SBML observable symbols to display labels."
}
]
},
"tags": [
"biomodels_ebi",
"curated",
"drug-response",
"faithful",
"immunotherapy",
"oncology",
"pharmacology",
"physiology",
"radiotherapy",
"sbml",
"systemsbiology",
"tumor-growth",
"virotherapy"
],
"title": "Al-Tuwairqi2020 - Dynamics of cancer radiovirotherapy - Phase II treatment Lab",
"models": [
{
"path": "owned/models/oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model",
"alias": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model",
"provenance": {
"owned_path": "owned/models/oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model"
}
},
{
"path": "owned/models/visualisation",
"alias": "visualisation",
"provenance": {
"owned_path": "owned/models/visualisation"
}
}
],
"wiring": [
{
"to": [
"visualisation.oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model_state"
],
"from": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.state"
},
{
"to": [
"visualisation.oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model_summary"
],
"from": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.summary"
},
{
"to": [
"visualisation.oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model_species_labels"
],
"from": "oncology_sbml_al_tuwairqi2020_dynamics_of_cancer_radiovirother_biomd0000001032_model.species_labels"
}
],
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"description": "This ordinary differential equation model of cancer radiovirotherapy dynamics is described in the publication:Salma M. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.",
"schema_version": "2.0"
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