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Chrobak2011 - A mathematical model of induced cancer-adaptive immune system competition Lab

About lab

This is a mathematical model describing competition between an artificially induced tumor and the adaptive immune system based on the use of an autonomous system of ordinary differential equations. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagechrobak2011-a-mathematical-model-of-induced-cancer-adaptive-immu
Created2026-05-15
Updated2026-05-15
immunologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_cancer",
        "label": "Initial Cancer",
        "units": "native source value",
        "default": 0.0005,
        "maps_to": "immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model.initial_cancer",
        "description": "Initial Cancer. Sets the initial value of bundled SBML species `x_Cancer`."
      },
      {
        "name": "initial_immune_system",
        "label": "Initial Immune System",
        "units": "native source value",
        "default": 0.01,
        "maps_to": "immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model.initial_immune_system",
        "description": "Initial Immune System. Sets the initial value of bundled SBML species `y_Immune_System`."
      }
    ],
    "outputs": [
      {
        "name": "cancer",
        "maps_to": "immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model.cancer"
      },
      {
        "name": "immune_system",
        "maps_to": "immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model.immune_system"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model.species_labels"
      }
    ]
  },
  "title": "Chrobak2011 - A mathematical model of induced cancer-adaptive immune system competition Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model",
      "alias": "immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model_state"
      ],
      "from": "immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model_summary"
      ],
      "from": "immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model_species_labels"
      ],
      "from": "immunology_sbml_chrobak2011_a_mathematical_model_of_induced_canc_biomd0000000815_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This is a mathematical model describing competition between an artificially induced tumor and the adaptive immune system based on the use of an autonomous system of ordinary differential equations. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}

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