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Courtemanche1998 - Mathematical Ionic Mechanisms Underlying Human Atrial Lab

About lab

Source-faithful physiology lab for Courtemanche, Ramirez, Nattel, 1998. Public controls and outputs are mapped to real source symbols for electrophysiology.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packagecourtemanche1998-mathematical-ionic-mechanisms-underlying-human
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_membrane_voltage_v",
        "label": "Initial Membrane Voltage V",
        "maps_to": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.initial_membrane_voltage_v",
        "description": "Initial value for Membrane Voltage V. Maps to source symbol `v`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "dimensionless"
        ]
      },
      {
        "name": "initial_membrane_voltage",
        "label": "Initial Membrane Voltage",
        "maps_to": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.initial_membrane_voltage",
        "description": "Initial value for Membrane Voltage. Maps to source symbol `V`. Units: millivolt. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "millivolt"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.variable_labels"
      },
      {
        "name": "membrane_voltage_v",
        "label": "Membrane Voltage V",
        "maps_to": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.membrane_voltage_v",
        "description": "Membrane Voltage V. Maps to source symbol `v`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "sodium_current_i_na_k",
        "label": "Sodium Current I Na K",
        "maps_to": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.sodium_current_i_na_k",
        "description": "Sodium Current I Na K. Maps to source symbol `i_NaK`. Units: picoA. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "sodium_current_i_na_k_max",
        "label": "Sodium Current I Na K Max",
        "maps_to": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.sodium_current_i_na_k_max",
        "description": "Sodium Current I Na K Max. Maps to source symbol `i_NaK_max`. Units: picoA_per_picoF. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "membrane_voltage",
        "label": "Membrane Voltage",
        "maps_to": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.membrane_voltage",
        "description": "Membrane Voltage. Maps to source symbol `V`. Units: millivolt. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "sodium_h_gate",
        "label": "Sodium H Gate",
        "maps_to": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.sodium_h_gate",
        "description": "Sodium H Gate. Maps to source symbol `h`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "sodium_j_gate",
        "label": "Sodium J Gate",
        "maps_to": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.sodium_j_gate",
        "description": "Sodium J Gate. Maps to source symbol `j`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      }
    ]
  },
  "title": "Courtemanche1998 - Mathematical Ionic Mechanisms Underlying Human Atrial Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model",
      "alias": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model",
      "parameters": {
        "model_path": "data/courtemanche_ramirez_nattel_1998.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model_state"
      ],
      "from": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model_summary"
      ],
      "from": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model_trajectory"
      ],
      "from": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model_variable_labels"
      ],
      "from": "physiology_cellml_courtemanche_ramirez_nattel_1998_courtemancheramireznattel1998_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Courtemanche, Ramirez, Nattel, 1998. Public controls and outputs are mapped to real source symbols for electrophysiology.",
  "schema_version": "2.0"
}

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