Moreno2019 - Stochastic model of G1 arrest due to proteostasis decline delimits replicative lifespan in yeast Lab

{
  "io": {
    "inputs": [
      {
        "name": "hsp104",
        "label": "Hsp104",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.hsp104",
        "description": "Controls Hsp104 in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.hsp104`."
      }
    ],
    "outputs": [
      {
        "name": "protein_load",
        "label": "Protein load",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.protein_load",
        "description": "Tracks Protein load in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.protein_load`."
      },
      {
        "name": "model_state_yp",
        "label": "Model state YP",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.model_state_yp",
        "description": "Tracks Model state YP in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.model_state_yp`."
      },
      {
        "name": "ydj1_chaperone",
        "label": "Ydj1 chaperone",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.ydj1_chaperone",
        "description": "Tracks Ydj1 chaperone in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.ydj1_chaperone`."
      },
      {
        "name": "prot_f",
        "label": "Prot F",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.prot_f",
        "description": "Tracks Prot F in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.prot_f`."
      },
      {
        "name": "prot_model_state_m",
        "label": "Prot Model state M",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.prot_model_state_m",
        "description": "Tracks Prot Model state M in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.prot_model_state_m`."
      },
      {
        "name": "oligomerized_proteostasis_species",
        "label": "Oligomerized proteostasis species",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.oligomerized_proteostasis_species",
        "description": "Tracks Oligomerized proteostasis species in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.oligomerized_proteostasis_species`."
      },
      {
        "name": "protein_aggregate_burden",
        "label": "Protein aggregate burden",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.protein_aggregate_burden",
        "description": "Tracks Protein aggregate burden in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.protein_aggregate_burden`."
      },
      {
        "name": "ydj1_oligomer_aggregate_complex",
        "label": "Ydj1-oligomer aggregate complex",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.ydj1_oligomer_aggregate_complex",
        "description": "Tracks Ydj1-oligomer aggregate complex in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.ydj1_oligomer_aggregate_complex`."
      },
      {
        "name": "model_state_ym",
        "label": "Model state YM",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.model_state_ym",
        "description": "Tracks Model state YM in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.model_state_ym`."
      },
      {
        "name": "model_state_yo",
        "label": "Model state YO",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.model_state_yo",
        "description": "Tracks Model state YO in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.model_state_yo`."
      },
      {
        "name": "cln3_start_cyclin",
        "label": "Cln3 Start cyclin",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.cln3_start_cyclin",
        "description": "Tracks Cln3 Start cyclin in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.cln3_start_cyclin`."
      },
      {
        "name": "model_state_yc",
        "label": "Model state YC",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.model_state_yc",
        "description": "Tracks Model state YC in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.model_state_yc`."
      },
      {
        "name": "folded_cln3_start_cyclin",
        "label": "Folded Cln3 Start cyclin",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.folded_cln3_start_cyclin",
        "description": "Tracks Folded Cln3 Start cyclin in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.folded_cln3_start_cyclin`."
      },
      {
        "name": "whi5_start_inhibitor",
        "label": "Whi5 Start inhibitor",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.whi5_start_inhibitor",
        "description": "Tracks Whi5 Start inhibitor in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.whi5_start_inhibitor`."
      },
      {
        "name": "inactive_whi5_start_inhibitor",
        "label": "Inactive Whi5 Start inhibitor",
        "maps_to": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.inactive_whi5_start_inhibitor",
        "description": "Tracks Inactive Whi5 Start inhibitor in the lab model via `cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.inactive_whi5_start_inhibitor`."
      }
    ]
  },
  "title": "Moreno2019 - Stochastic model of G1 arrest due to proteostasis decline delimits replicative lifespan in yeast Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model_state"
      ],
      "from": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.state"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model_summary"
      ],
      "from": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.summary"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model_species_labels"
      ],
      "from": "cellcycle_sbml_moreno2019_stochastic_model_of_g1_arrest_due_to_model1901210001_model.species_labels"
    }
  ],
  "package": "moreno2019-g1-arrest-proteostasis",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "Single-model lab wrapper for Moreno2019 - Stochastic model of G1 arrest due to proteostasis decline delimits replicative lifespan in yeast. This model is described within the paper: A G1 arrest due to proteostasis decline delimits replicative lifespan in yeastDavid F. Moreno, Kirsten Jenkins, Sandrine Morlot, Gilles Charvin, Attila Csik\\u00e1s.",
  "schema_version": "2.0"
}