Tiwari2019 - Mathematical model of NFKB regulatory module with TNF and ROS Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_tnf_receptor_level",
        "label": "TNF receptor",
        "maps_to": "signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model.initial_tnf_receptor_level",
        "description": "TNF receptor source parameter. Maps to SBML symbol `TNF_R` and preserves the bundled default."
      },
      {
        "name": "initial_tnf",
        "label": "Initial TNF",
        "maps_to": "signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model.initial_tnf",
        "description": "Initial level of TNF. Maps to SBML symbol `TNF`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "ikk_active",
        "label": "IKK active",
        "maps_to": "signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model.ikk_active",
        "description": "IKK active. Maps to SBML symbol `IKK_active` and is emitted in native SBML units."
      },
      {
        "name": "ikkactive_ik_b",
        "label": "Ikkactive Ik B",
        "maps_to": "signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model.ikkactive_ik_b",
        "description": "Ikkactive Ik B. Maps to SBML symbol `IKKactive_IkB` and is emitted in native SBML units."
      },
      {
        "name": "ikkactive_ik_b_nfkb",
        "label": "Ikkactive Ik B NF-kB",
        "maps_to": "signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model.ikkactive_ik_b_nfkb",
        "description": "Ikkactive Ik B NF-kB. Maps to SBML symbol `IKKactive_IkB_NFKB` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "nfkb",
    "tnf-signaling"
  ],
  "title": "Tiwari2019 - Mathematical model of NFKB regulatory module with TNF and ROS Lab",
  "models": [
    {
      "path": "owned/models/signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model",
      "alias": "signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model",
      "provenance": {
        "owned_path": "owned/models/signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model_state"
      ],
      "from": "signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model_summary"
      ],
      "from": "signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model_species_labels"
      ],
      "from": "signaling_sbml_tiwari2019_mathematical_model_of_nfkb_regulatory_model1911140002_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Clean Biosimulant lab for NF-kB pathway signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}