McDougal2017 - Metabolism in ischemic cardiomyocytes Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_h_super_plus_endsuper_sub_i_endsub",
        "units": "native SBML value",
        "default": 0.0000794,
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.initial_h_super_plus_endsuper_sub_i_endsub",
        "description": "Initial condition for h super plus endsuper sub i endsub. Maps to bundled SBML symbol `s1`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_h_super_plus_endsuper_sub_o_endsub",
        "units": "native SBML value",
        "default": "1e-12",
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.initial_h_super_plus_endsuper_sub_o_endsub",
        "description": "Initial condition for h super plus endsuper sub o endsub. Maps to bundled SBML symbol `s2`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_oh_super_minus_endsuper_sub_i_endsub",
        "units": "native SBML value",
        "default": "1e-12",
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.initial_oh_super_minus_endsuper_sub_i_endsub",
        "description": "Initial condition for oh super minus endsuper sub i endsub. Maps to bundled SBML symbol `s7`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_oh_super_minus_endsuper_sub_o_endsub",
        "units": "native SBML value",
        "default": "1e-12",
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.initial_oh_super_minus_endsuper_sub_o_endsub",
        "description": "Initial condition for oh super minus endsuper sub o endsub. Maps to bundled SBML symbol `s8`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_na_super_plus_endsuper_sub_i_endsub",
        "units": "native SBML value",
        "default": 5,
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.initial_na_super_plus_endsuper_sub_i_endsub",
        "description": "Initial condition for na super plus endsuper sub i endsub. Maps to bundled SBML symbol `s24`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      }
    ],
    "outputs": [
      {
        "name": "h_super_plus_endsuper_sub_i_endsub",
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.h_super_plus_endsuper_sub_i_endsub"
      },
      {
        "name": "h_super_plus_endsuper_sub_o_endsub",
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.h_super_plus_endsuper_sub_o_endsub"
      },
      {
        "name": "oh_super_minus_endsuper_sub_i_endsub",
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.oh_super_minus_endsuper_sub_i_endsub"
      },
      {
        "name": "oh_super_minus_endsuper_sub_o_endsub",
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.oh_super_minus_endsuper_sub_o_endsub"
      },
      {
        "name": "na_super_plus_endsuper_sub_i_endsub",
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.na_super_plus_endsuper_sub_i_endsub"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.observable_labels"
      }
    ]
  },
  "title": "McDougal2017 - Metabolism in ischemic cardiomyocytes Lab",
  "models": [
    {
      "path": "owned/models/metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model",
      "alias": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model",
      "parameters": {
        "model_path": "data/BIOMD0000000961.xml",
        "integration_step": 0.1
      },
      "provenance": {
        "owned_path": "owned/models/metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model_observable_values"
      ],
      "from": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model_run_summary"
      ],
      "from": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model_observable_labels"
      ],
      "from": "metabolism_sbml_mcdougal2017_metabolism_in_ischemic_cardiomyocyt_biomd0000000961_model.observable_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "Heart disease remains the leading cause of death globally. Although reperfusion following myocardial ischemia can prevent death by restoring nutrient flow, ischemia/reperfusion injury can cause signif.",
  "schema_version": "2.0"
}