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Waugh2007 - Sherratt Mathematical Macrophage Dynamics Diabetic Wound Lab

About lab

Source-faithful physiology lab for Waugh, Sherratt, 2007. Public controls and outputs are mapped to real source symbols for source-model physiology.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packagewaugh2007-sherratt-mathematical-macrophage-dynamics-diabetic-wou
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_collagen_concentration",
        "label": "Initial Collagen Concentration",
        "maps_to": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.initial_collagen_concentration",
        "description": "Initial value for Collagen Concentration. Maps to source symbol `C`. Units: microg_per_mm3. Naming evidence: source metadata names `C` as `collagen concentration`.",
        "accepted_units": [
          "microg_per_mm3"
        ]
      },
      {
        "name": "initial_fibroblast_density",
        "label": "Initial Fibroblast Density",
        "maps_to": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.initial_fibroblast_density",
        "description": "Initial value for Fibroblast Density. Maps to source symbol `F`. Units: cells_per_mm3. Naming evidence: source metadata names `F` as `fibroblast density`.",
        "accepted_units": [
          "cells_per_mm3"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.variable_labels"
      },
      {
        "name": "collagen_concentration",
        "label": "Collagen Concentration",
        "maps_to": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.collagen_concentration",
        "description": "Collagen Concentration. Maps to source symbol `C`. Units: microg_per_mm3. Naming evidence: source metadata names `C` as `collagen concentration`."
      },
      {
        "name": "fibroblast_density",
        "label": "Fibroblast Density",
        "maps_to": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.fibroblast_density",
        "description": "Fibroblast Density. Maps to source symbol `F`. Units: cells_per_mm3. Naming evidence: source metadata names `F` as `fibroblast density`."
      },
      {
        "name": "hyaluronan_concentration",
        "label": "Hyaluronan Concentration",
        "maps_to": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.hyaluronan_concentration",
        "description": "Hyaluronan Concentration. Maps to source symbol `H`. Units: microg_per_mm3. Naming evidence: source metadata names `H` as `hyaluronan concentration`."
      },
      {
        "name": "pdgf_concentration",
        "label": "Pdgf Concentration",
        "maps_to": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.pdgf_concentration",
        "description": "Pdgf Concentration. Maps to source symbol `P`. Units: pg_per_mm3. Naming evidence: source metadata names `P` as `PDGF concentration`."
      },
      {
        "name": "inflammatory_macrophage_cell_density",
        "label": "Inflammatory Macrophage Cell Density",
        "maps_to": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.inflammatory_macrophage_cell_density",
        "description": "Inflammatory Macrophage Cell Density. Maps to source symbol `phi_I`. Units: cells_per_mm3. Naming evidence: source metadata names `phi_I` as `inflammatory macrophage cell density`."
      },
      {
        "name": "transforming_growth_factor_beta_concentration",
        "label": "Transforming Growth Factor Beta Concentration",
        "maps_to": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.transforming_growth_factor_beta_concentration",
        "description": "Transforming Growth Factor Beta Concentration. Maps to source symbol `T`. Units: pg_per_mm3. Naming evidence: source metadata names `T` as `transforming growth factor-beta concentration`."
      }
    ]
  },
  "title": "Waugh2007 - Sherratt Mathematical Macrophage Dynamics Diabetic Wound Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model",
      "alias": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model",
      "parameters": {
        "model_path": "data/waugh_sherratt_2007_a.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model_state"
      ],
      "from": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model_summary"
      ],
      "from": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model_trajectory"
      ],
      "from": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model_variable_labels"
      ],
      "from": "physiology_cellml_waugh_sherratt_2007_waughsherratt2007_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Waugh, Sherratt, 2007. Public controls and outputs are mapped to real source symbols for source-model physiology.",
  "schema_version": "2.0"
}

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