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Proctor2012 Role Of Amyloid Beta Dimers In Aggregation Formation Lab

About lab

Proctor2012 - Amyloid-beta aggregation This model supports the current thinking that levels of dimers are important in initiating the aggregation process. This model is described in the article: Aggre.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packageproctor2012-role-of-amyloid-beta-dimers-in-aggregation-formation
Created2026-05-17
Updated2026-05-17
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_neprilysin",
        "label": "Initial Neprilysin",
        "maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.initial_neprilysin",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Nep`."
      },
      {
        "name": "initial_abeta_plaque",
        "label": "Initial Abeta Plaque",
        "maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.initial_abeta_plaque",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `AbP`."
      },
      {
        "name": "initial_abeta_monomer",
        "label": "Initial Abeta Monomer",
        "maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.initial_abeta_monomer",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Abeta`."
      },
      {
        "name": "initial_abeta_dimer",
        "label": "Initial Abeta Dimer",
        "maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.initial_abeta_dimer",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `AbDim`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.species_labels"
      },
      {
        "name": "neprilysin",
        "maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.neprilysin"
      },
      {
        "name": "abeta_plaque",
        "maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.abeta_plaque"
      },
      {
        "name": "abeta_monomer",
        "maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.abeta_monomer"
      },
      {
        "name": "abeta_dimer",
        "maps_to": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.abeta_dimer"
      }
    ]
  },
  "tags": [
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Proctor2012 Role Of Amyloid Beta Dimers In Aggregation Formation Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model",
      "alias": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model_state"
      ],
      "from": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model_summary"
      ],
      "from": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model_species_labels"
      ],
      "from": "systemsbiology_sbml_proctor2012_role_of_amyloid_beta_dimers_in_aggre_biomd0000000462_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Proctor2012 - Amyloid-beta aggregation This model supports the current thinking that levels of dimers are important in initiating the aggregation process. This model is described in the article: Aggre.",
  "schema_version": "2.0"
}

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