About lab
End-to-end shear-stress driven mechanotransduction. Composes the calcium-influx submodel with the NO-production submodel by wiring the cytosolic calcium output of the first into the cytosolic calcium input of the second. Single experimental knob: stimulus_intensity.
Runtime
Duration600
Comms Step10
Runs
Total3
Completed2
Failed1
Metadata
Packagekoo2013-shear-to-no-composed-pathway
Created2026-05-04
Updated2026-05-14
biomechanicsendothelialshear-stressmechanotransductioncalciumsbmlbiomodels_ebifaithfulnitric-oxidevisualisationkoo2013
Manifest
{
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{
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{
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{
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]
},
"title": "Koo2013 Shear-to-NO Composed Pathway",
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},
"description": "End-to-end shear-stress driven mechanotransduction. Composes the calcium-influx submodel with the NO-production submodel by wiring the cytosolic calcium output of the first into the cytosolic calcium input of the second. Single experimental knob: stimulus_intensity.",
"schema_version": "2.0"
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JSON
{
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"rows": [
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"title": "What Happened"
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"description": "What did this simulation actually show, in plain language?",
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[
"What did this run track?",
"16 observables in Koo2013 Shear-Stress Induced NO Production"
],
[
"How long did it run?",
"590 s"
],
[
"Which observable changed the most?",
"Nitric oxide"
],
[
"Largest peak?",
"Hsp90"
]
],
"title": "What Happened"
},
"description": "What did this simulation actually show, in plain language?",
"render": "table"
}
]
}
]
}