Li2016 - Model for pancreatic cancer patients receiving immunotherapy Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_pancreatic_cancer_cells_c",
        "label": "Pancreatic cancer cells (C)",
        "units": "native SBML value",
        "default": 1000000000,
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.initial_pancreatic_cancer_cells_c",
        "description": "Initial Pancreatic cancer cells (C). Sets the initial value of bundled SBML symbol `Pancreatic_cancer_cells__C`."
      },
      {
        "name": "initial_pancreatic_stellate_cells_p",
        "label": "Pancreatic stellate cells (P)",
        "units": "native SBML value",
        "default": 5600000,
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.initial_pancreatic_stellate_cells_p",
        "description": "Initial Pancreatic stellate cells (P). Sets the initial value of bundled SBML symbol `Pancreatic_stellate_cells__P`."
      },
      {
        "name": "initial_cd8_t_cells_t",
        "label": "CD8+ T cells (T)",
        "units": "native SBML value",
        "default": 700000000,
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.initial_cd8_t_cells_t",
        "description": "Initial CD8+ T cells (T). Sets the initial value of bundled SBML symbol `CD8__T_cells__T`."
      },
      {
        "name": "initial_nk_cells_n",
        "label": "NK cells (N)",
        "units": "native SBML value",
        "default": 352800000,
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.initial_nk_cells_n",
        "description": "Initial NK cells (N). Sets the initial value of bundled SBML symbol `NK_cells__N`."
      },
      {
        "name": "initial_helper_t_cells_h",
        "label": "Helper T cells (H)",
        "units": "native SBML value",
        "default": 1881600000,
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.initial_helper_t_cells_h",
        "description": "Initial Helper T cells (H). Sets the initial value of bundled SBML symbol `helper_T_cells__H`."
      }
    ],
    "outputs": [
      {
        "name": "pancreatic_cancer_cells_c",
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.pancreatic_cancer_cells_c",
        "description": "Pancreatic cancer cells (C) observable. Maps to SBML symbol `Pancreatic_cancer_cells__C`."
      },
      {
        "name": "pancreatic_stellate_cells_p",
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.pancreatic_stellate_cells_p",
        "description": "Pancreatic stellate cells (P) observable. Maps to SBML symbol `Pancreatic_stellate_cells__P`."
      },
      {
        "name": "cd8_t_cells_t",
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.cd8_t_cells_t",
        "description": "CD8+ T cells (T) observable. Maps to SBML symbol `CD8__T_cells__T`."
      },
      {
        "name": "nk_cells_n",
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.nk_cells_n",
        "description": "NK cells (N) observable. Maps to SBML symbol `NK_cells__N`."
      },
      {
        "name": "helper_t_cells_h",
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.helper_t_cells_h",
        "description": "Helper T cells (H) observable. Maps to SBML symbol `helper_T_cells__H`."
      },
      {
        "name": "state",
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.state",
        "description": "Full raw SBML observable record for reproducibility and downstream visualisation."
      },
      {
        "name": "summary",
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.summary",
        "description": "Change and peak summary across the simulated SBML observables."
      },
      {
        "name": "species_labels",
        "maps_to": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.species_labels",
        "description": "Mapping from selected raw SBML observable symbols to display labels."
      }
    ]
  },
  "tags": [
    "biomodels_ebi",
    "curated",
    "drug-response",
    "faithful",
    "immunology",
    "immunotherapy",
    "microenvironment",
    "oncology",
    "pharmacology",
    "physiology",
    "sbml",
    "systemsbiology",
    "tumor-growth"
  ],
  "title": "Li2016 - Model for pancreatic cancer patients receiving immunotherapy Lab",
  "models": [
    {
      "path": "owned/models/oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model",
      "alias": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model",
      "provenance": {
        "owned_path": "owned/models/oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model_state"
      ],
      "from": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.state"
    },
    {
      "to": [
        "visualisation.oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model_summary"
      ],
      "from": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.summary"
    },
    {
      "to": [
        "visualisation.oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model_species_labels"
      ],
      "from": "oncology_sbml_li2016_model_for_pancreatic_cancer_patients_rece_biomd0000000929_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "immunotherapy offers a better prognosis for pancreatic cancer patients. As a direct extension of this work, various new therapy methods that are under exploration and clinical trials could be assessed.",
  "schema_version": "2.0"
}