Konrath2020 P53 Signaling Lab

{
  "io": {
    "inputs": [
      {
        "name": "dna_damage_signal",
        "label": "DNA damage signal",
        "maps_to": "konrath2020_p53_signaling.dna_damage_signal",
        "description": "Source parameter `damage`, used as the DNA-damage stimulus in the p53 signaling model."
      }
    ],
    "outputs": [
      {
        "name": "p53",
        "maps_to": "konrath2020_p53_signaling.p53"
      },
      {
        "name": "active_p53",
        "maps_to": "konrath2020_p53_signaling.active_p53"
      },
      {
        "name": "mdm2",
        "maps_to": "konrath2020_p53_signaling.mdm2"
      },
      {
        "name": "phosphorylated_atm",
        "maps_to": "konrath2020_p53_signaling.phosphorylated_atm"
      },
      {
        "name": "state",
        "maps_to": "konrath2020_p53_signaling.state"
      },
      {
        "name": "summary",
        "maps_to": "konrath2020_p53_signaling.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "konrath2020_p53_signaling.species_labels"
      }
    ]
  },
  "title": "Konrath2020 P53 Signaling Lab",
  "models": [
    {
      "path": "owned/models/konrath2020_p53_signaling",
      "alias": "konrath2020_p53_signaling",
      "parameters": {
        "model_path": "data/MODEL2004300002.xml",
        "integration_step": 0.1
      },
      "provenance": {
        "owned_path": "owned/models/konrath2020_p53_signaling"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.konrath2020_p53_signaling_p53"
      ],
      "from": "konrath2020_p53_signaling.p53"
    },
    {
      "to": [
        "visualisation.konrath2020_p53_signaling_active_p53"
      ],
      "from": "konrath2020_p53_signaling.active_p53"
    },
    {
      "to": [
        "visualisation.konrath2020_p53_signaling_mdm2"
      ],
      "from": "konrath2020_p53_signaling.mdm2"
    },
    {
      "to": [
        "visualisation.konrath2020_p53_signaling_phosphorylated_atm"
      ],
      "from": "konrath2020_p53_signaling.phosphorylated_atm"
    },
    {
      "to": [
        "visualisation.konrath2020_p53_signaling_state"
      ],
      "from": "konrath2020_p53_signaling.state"
    },
    {
      "to": [
        "visualisation.konrath2020_p53_signaling_summary"
      ],
      "from": "konrath2020_p53_signaling.summary"
    },
    {
      "to": [
        "visualisation.konrath2020_p53_signaling_species_labels"
      ],
      "from": "konrath2020_p53_signaling.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "p53 subpopulation signaling. The ODE model is based on Batchelor et al., Mol. It can be used to explore generegulation konrath2020 p53 signaling model2004300002 dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}