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Mitrophanov2013 Simulation Of Hockin Blood Coagulation Model Under Reduced Lab

About lab

Blood coagulation model using an updated Hockin2002 model. New reactions for factor X and V activation by IXa and mIIa respectively (reactions R28 and R29, parameters k43 and k44).

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packagemitrophanov2013-simulation-of-hockin-blood-coagulation-model-und
Created2026-05-17
Updated2026-05-17
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_m_i_ia_atiii",
        "label": "Initial M I Ia Atiii",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.initial_m_i_ia_atiii",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mIIa_ATIII`."
      },
      {
        "name": "initial_m_i_ia",
        "label": "Initial M I Ia",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.initial_m_i_ia",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mIIa`."
      },
      {
        "name": "initial_xa_va_ii",
        "label": "Initial Xa Va Ii",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.initial_xa_va_ii",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_Va_II`."
      },
      {
        "name": "initial_xa_va",
        "label": "Initial Xa Va",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.initial_xa_va",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_Va`."
      },
      {
        "name": "initial_xa_tfpi",
        "label": "Initial Xa Tfpi",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.initial_xa_tfpi",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_TFPI`."
      },
      {
        "name": "initial_xa_atiii",
        "label": "Initial Xa Atiii",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.initial_xa_atiii",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Xa_ATIII`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.species_labels"
      },
      {
        "name": "m_i_ia_atiii",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.m_i_ia_atiii"
      },
      {
        "name": "m_i_ia",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.m_i_ia"
      },
      {
        "name": "xa_va_ii",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.xa_va_ii"
      },
      {
        "name": "xa_va",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.xa_va"
      },
      {
        "name": "xa_tfpi",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.xa_tfpi"
      },
      {
        "name": "xa_atiii",
        "maps_to": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.xa_atiii"
      }
    ]
  },
  "tags": [
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Mitrophanov2013 Simulation Of Hockin Blood Coagulation Model Under Reduced Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model",
      "alias": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
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      ],
      "from": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.state"
    },
    {
      "to": [
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      ],
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    },
    {
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      ],
      "from": "systemsbiology_sbml_mitrophanov2013_simulation_of_hockin_blood_coagu_model1806250002_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Blood coagulation model using an updated Hockin2002 model. New reactions for factor X and V activation by IXa and mIIa respectively (reactions R28 and R29, parameters k43 and k44).",
  "schema_version": "2.0"
}

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