Sobotta2017 - IL-6-induced JAK1-STAT3-signaling Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_input_rux1_level",
        "label": "Input Rux1",
        "maps_to": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model.initial_input_rux1_level",
        "description": "Input Rux1 source parameter. Maps to SBML symbol `input_rux1` and preserves the bundled default."
      },
      {
        "name": "initial_input_rux2_level",
        "label": "Input Rux2",
        "maps_to": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model.initial_input_rux2_level",
        "description": "Input Rux2 source parameter. Maps to SBML symbol `input_rux2` and preserves the bundled default."
      },
      {
        "name": "initial_input_rux3_level",
        "label": "Input Rux3",
        "maps_to": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model.initial_input_rux3_level",
        "description": "Input Rux3 source parameter. Maps to SBML symbol `input_rux3` and preserves the bundled default."
      }
    ],
    "outputs": [
      {
        "name": "unphosphorylated_receptor",
        "label": "Unphosphorylated Receptor",
        "maps_to": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model.unphosphorylated_receptor",
        "description": "Unphosphorylated Receptor. Maps to SBML symbol `JAK1_gp130` and is emitted in native SBML units."
      },
      {
        "name": "phosphorylated_jak1_receptor",
        "label": "Phosphorylated JAK1 Receptor",
        "maps_to": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model.phosphorylated_jak1_receptor",
        "description": "Phosphorylated JAK1 Receptor. Maps to SBML symbol `pJAK1_gp130` and is emitted in native SBML units."
      },
      {
        "name": "active_receptor",
        "label": "active Receptor",
        "maps_to": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model.active_receptor",
        "description": "active Receptor. Maps to SBML symbol `pJAK1_pgp130` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "cytokine-signaling",
    "jak-stat",
    "interleukin-signaling"
  ],
  "title": "Sobotta2017 - IL-6-induced JAK1-STAT3-signaling Lab",
  "models": [
    {
      "path": "owned/models/signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model",
      "alias": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model",
      "provenance": {
        "owned_path": "owned/models/signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model_state"
      ],
      "from": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model_summary"
      ],
      "from": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model_species_labels"
      ],
      "from": "signaling_sbml_sobotta2017_il_6_induced_jak1_stat3_signaling_model2307050001_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Clean Biosimulant lab for JAK/STAT cytokine signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}