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Mothes2020 Nfkb A20 Signaling Lab

About lab

The Mothes2020_NFkB_A20_signaling model is based on our previous model published in Murakawa et al., Nat Commun, 2015 (doi: 10.1038/ncomms8367). It can be used to explore systemsbiology mothes2020 nfkb a20 signaling model2307110001 dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packagemothes2020-nfkb-a20-signaling-lab
Created2026-05-17
Updated2026-05-17
signalingsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "stimulus",
        "label": "Stimulus",
        "maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.stimulus",
        "description": "Source parameter exposed because its SBML label indicates a boundary, stimulus, dose, ligand, protocol, substrate, or environmental control. Maps to SBML symbol `stimulus`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.species_labels"
      },
      {
        "name": "a20_mrna",
        "maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.a20_mrna"
      },
      {
        "name": "ik_ba_mrna",
        "maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.ik_ba_mrna"
      },
      {
        "name": "n_fk_b_ik_ba",
        "maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.n_fk_b_ik_ba"
      },
      {
        "name": "ik_ba",
        "maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.ik_ba"
      },
      {
        "name": "a20",
        "maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.a20"
      },
      {
        "name": "ikk_active",
        "maps_to": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.ikk_active"
      }
    ]
  },
  "tags": [
    "signaling",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Mothes2020 Nfkb A20 Signaling Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model",
      "alias": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model_state"
      ],
      "from": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model_summary"
      ],
      "from": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model_species_labels"
      ],
      "from": "systemsbiology_sbml_mothes2020_nfkb_a20_signaling_model2307110001_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "The Mothes2020_NFkB_A20_signaling model is based on our previous model published in Murakawa et al., Nat Commun, 2015 (doi: 10.1038/ncomms8367). It can be used to explore systemsbiology mothes2020 nfkb a20 signaling model2307110001 dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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