Albeck2008 Extrinsic Apoptosis Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_cyto_c_m",
        "label": "Initial Cyto C M",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.initial_cyto_c_m",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `CytoCm`."
      },
      {
        "name": "initial_pro_c9",
        "label": "Initial Pro C9",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.initial_pro_c9",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `pC9`."
      },
      {
        "name": "initial_smac_m",
        "label": "Initial Smac M",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.initial_smac_m",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Smacm`."
      },
      {
        "name": "initial_pro_c8",
        "label": "Initial Pro C8",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.initial_pro_c8",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `pC8`."
      },
      {
        "name": "initial_cytosolic_bcl_2",
        "label": "Initial Cytosolic Bcl 2",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.initial_cytosolic_bcl_2",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Bcl2c`."
      },
      {
        "name": "initial_bcl_2",
        "label": "Initial Bcl 2",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.initial_bcl_2",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Bcl2`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.species_labels"
      },
      {
        "name": "cyto_c_m",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.cyto_c_m"
      },
      {
        "name": "pro_c9",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.pro_c9"
      },
      {
        "name": "smac_m",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.smac_m"
      },
      {
        "name": "pro_c8",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.pro_c8"
      },
      {
        "name": "cytosolic_bcl_2",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.cytosolic_bcl_2"
      },
      {
        "name": "bcl_2",
        "maps_to": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.bcl_2"
      }
    ]
  },
  "tags": [
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Albeck2008 Extrinsic Apoptosis Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model",
      "alias": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model_state"
      ],
      "from": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model_summary"
      ],
      "from": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model_species_labels"
      ],
      "from": "systemsbiology_sbml_albeck2008_extrinsic_apoptosis_biomd0000000220_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "This the model used in the article: Quantitative analysis of pathways controlling extrinsic apoptosis in single cells. Albeck JG, Burke JM, Aldridge BB, Zhang M, Lauffenburger DA, Sorger PK.",
  "schema_version": "2.0"
}