Capuani2015 - Binding of Cbl and Gbr2 to EGFR (Multisite Phosphorylation Model - MPM) Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_cbl_ubiquitin_ligase_factor_level",
        "label": "Cbl ubiquitin ligase Factor",
        "maps_to": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model.initial_cbl_ubiquitin_ligase_factor_level",
        "description": "Cbl ubiquitin ligase Factor source parameter. Maps to SBML symbol `CblFactor` and preserves the bundled default."
      },
      {
        "name": "initial_egfr_00uu",
        "label": "Initial EGFR 00UU",
        "maps_to": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model.initial_egfr_00uu",
        "description": "Initial level of EGFR 00UU. Maps to SBML symbol `EGFR_00UU`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_egfr_01ug",
        "label": "Initial EGFR 01UG",
        "maps_to": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model.initial_egfr_01ug",
        "description": "Initial level of EGFR 01UG. Maps to SBML symbol `EGFR_01UG`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "cbl_ubiquitin_ligase",
        "label": "Cbl ubiquitin ligase",
        "maps_to": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model.cbl_ubiquitin_ligase",
        "description": "Cbl ubiquitin ligase. Maps to SBML symbol `Cbl` and is emitted in native SBML units."
      },
      {
        "name": "grb2_adapter_protein",
        "label": "Grb2 adapter protein",
        "maps_to": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model.grb2_adapter_protein",
        "description": "Grb2 adapter protein. Maps to SBML symbol `Grb2` and is emitted in native SBML units."
      },
      {
        "name": "tyrosine_site",
        "label": "tyrosine site",
        "maps_to": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model.tyrosine_site",
        "description": "tyrosine site. Maps to SBML symbol `Tyr` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "egfr"
  ],
  "title": "Capuani2015 - Binding of Cbl and Gbr2 to EGFR (Multisite Phosphorylation Model - MPM) Lab",
  "models": [
    {
      "path": "owned/models/signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model",
      "alias": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model",
      "provenance": {
        "owned_path": "owned/models/signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model_state"
      ],
      "from": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model_summary"
      ],
      "from": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model_species_labels"
      ],
      "from": "signaling_sbml_capuani2015_binding_of_cbl_and_gbr2_to_egfr_mult_biomd0000000594_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Clean Biosimulant lab for MAPK/ERK receptor signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}