BiosimulantBiosimulant
Docs
Search labs...
Sign inGet Started

Physiome 1cd - Notch Signaling Pathway Lab

About lab

Source-faithful physiology lab for Notch signaling pathway. Public controls and outputs are mapped to real source symbols for signalling physiology.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packagephysiome-1cd-notch-signaling-pathway-lab
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_dll1",
        "label": "Initial Dll1",
        "maps_to": "physiology_cellml_notch_signaling_pathway_1cd_model.initial_dll1",
        "description": "Initial value for Dll1. Maps to source symbol `Dll1`. Units: nM. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "nM"
        ]
      },
      {
        "name": "initial_hes7_c",
        "label": "Initial Hes7 C",
        "maps_to": "physiology_cellml_notch_signaling_pathway_1cd_model.initial_hes7_c",
        "description": "Initial value for Hes7 C. Maps to source symbol `Hes7_c`. Units: nM. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "nM"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_notch_signaling_pathway_1cd_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_notch_signaling_pathway_1cd_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_notch_signaling_pathway_1cd_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_notch_signaling_pathway_1cd_model.variable_labels"
      },
      {
        "name": "dll1",
        "label": "Dll1",
        "maps_to": "physiology_cellml_notch_signaling_pathway_1cd_model.dll1",
        "description": "Dll1. Maps to source symbol `Dll1`. Units: nM. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "hes7_c",
        "label": "Hes7 C",
        "maps_to": "physiology_cellml_notch_signaling_pathway_1cd_model.hes7_c",
        "description": "Hes7 C. Maps to source symbol `Hes7_c`. Units: nM. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "hes7_n",
        "label": "Hes7 N",
        "maps_to": "physiology_cellml_notch_signaling_pathway_1cd_model.hes7_n",
        "description": "Hes7 N. Maps to source symbol `Hes7_n`. Units: nM. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "lfng",
        "label": "Lfng",
        "maps_to": "physiology_cellml_notch_signaling_pathway_1cd_model.lfng",
        "description": "Lfng. Maps to source symbol `Lfng`. Units: nM. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "m_hes7_c",
        "label": "M Hes7 C",
        "maps_to": "physiology_cellml_notch_signaling_pathway_1cd_model.m_hes7_c",
        "description": "M Hes7 C. Maps to source symbol `mHes7_c`. Units: nM. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "m_hes7_n",
        "label": "M Hes7 N",
        "maps_to": "physiology_cellml_notch_signaling_pathway_1cd_model.m_hes7_n",
        "description": "M Hes7 N. Maps to source symbol `mHes7_n`. Units: nM. Naming evidence: source symbol, component, or units provide a direct public name."
      }
    ]
  },
  "title": "Physiome 1cd - Notch Signaling Pathway Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_notch_signaling_pathway_1cd_model",
      "alias": "physiology_cellml_notch_signaling_pathway_1cd_model",
      "parameters": {
        "model_path": "data/Notch_1_Wang.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_notch_signaling_pathway_1cd_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_notch_signaling_pathway_1cd_model_state"
      ],
      "from": "physiology_cellml_notch_signaling_pathway_1cd_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_notch_signaling_pathway_1cd_model_summary"
      ],
      "from": "physiology_cellml_notch_signaling_pathway_1cd_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_notch_signaling_pathway_1cd_model_trajectory"
      ],
      "from": "physiology_cellml_notch_signaling_pathway_1cd_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_notch_signaling_pathway_1cd_model_variable_labels"
      ],
      "from": "physiology_cellml_notch_signaling_pathway_1cd_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Notch signaling pathway. Public controls and outputs are mapped to real source symbols for signalling physiology.",
  "schema_version": "2.0"
}

Sign in to start your own run. Public-lab history stays visible here.

Select a run from History to view its results.