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Mears1997 Crac Pancreaticbetacells Lab

About lab

This a model from the article: Evidence that calcium release-activated current mediates the biphasic electricalactivity of mouse pancreatic beta-cells. Mears D, Sheppard NF Jr, Atwater I, Rojas E, Ber.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packagemears1997-crac-pancreaticbetacells-lab
Created2026-05-17
Updated2026-05-17
physiologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_v_membrane",
        "label": "Initial V Membrane",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.initial_v_membrane",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `V_membrane`."
      },
      {
        "name": "initial_ca_er_ca_equations",
        "label": "Initial Ca Er Ca Equations",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.initial_ca_er_ca_equations",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ca_er_Ca_equations`."
      },
      {
        "name": "initial_model_state_jm",
        "label": "Initial Model State Jm",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.initial_model_state_jm",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `jm`."
      },
      {
        "name": "initial_ca_i",
        "label": "Initial Ca I",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.initial_ca_i",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ca_i`."
      },
      {
        "name": "initial_model_state_n",
        "label": "Initial Model State N",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.initial_model_state_n",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `n`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.species_labels"
      },
      {
        "name": "v_membrane",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.v_membrane"
      },
      {
        "name": "ca_er_ca_equations",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.ca_er_ca_equations"
      },
      {
        "name": "model_state_jm",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.model_state_jm"
      },
      {
        "name": "ca_i",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.ca_i"
      },
      {
        "name": "model_state_n",
        "maps_to": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.model_state_n"
      }
    ]
  },
  "tags": [
    "physiology",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Mears1997 Crac Pancreaticbetacells Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model",
      "alias": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model_state"
      ],
      "from": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model_summary"
      ],
      "from": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model_species_labels"
      ],
      "from": "systemsbiology_sbml_mears1997_crac_pancreaticbetacells_biomd0000000375_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "This a model from the article: Evidence that calcium release-activated current mediates the biphasic electricalactivity of mouse pancreatic beta-cells. Mears D, Sheppard NF Jr, Atwater I, Rojas E, Ber.",
  "schema_version": "2.0"
}

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