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Physiome b0d - Serca Three State Lab

About lab

Source-faithful physiology lab for SERCA_ThreeState. Public controls and outputs are mapped to real source symbols for calcium handling.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packagephysiome-b0d-serca-three-state-lab
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_ca_sr",
        "label": "Initial Ca Sr",
        "maps_to": "physiology_cellml_serca_threestate_b0d_model.initial_ca_sr",
        "description": "Initial value for Ca Sr. Maps to source symbol `Ca_sr`. Units: millimolar. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "millimolar"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_serca_threestate_b0d_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_serca_threestate_b0d_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_serca_threestate_b0d_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_serca_threestate_b0d_model.variable_labels"
      },
      {
        "name": "atp_concentration",
        "label": "ATP Concentration",
        "maps_to": "physiology_cellml_serca_threestate_b0d_model.atp_concentration",
        "description": "ATP Concentration. Maps to source symbol `ATP`. Units: millimolar. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "adp_concentration",
        "label": "ADP Concentration",
        "maps_to": "physiology_cellml_serca_threestate_b0d_model.adp_concentration",
        "description": "ADP Concentration. Maps to source symbol `ADP`. Units: millimolar. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "ca_sr",
        "label": "Ca Sr",
        "maps_to": "physiology_cellml_serca_threestate_b0d_model.ca_sr",
        "description": "Ca Sr. Maps to source symbol `Ca_sr`. Units: millimolar. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "concentration_h_i",
        "label": "Concentration H I (source H_i)",
        "maps_to": "physiology_cellml_serca_threestate_b0d_model.concentration_h_i",
        "description": "Concentration H I (source H_i). Maps to source symbol `H_i`. Units: millimolar. Naming evidence: amount concentration units identify a concentration state."
      },
      {
        "name": "concentration_p_i",
        "label": "Concentration P I (source P_i)",
        "maps_to": "physiology_cellml_serca_threestate_b0d_model.concentration_p_i",
        "description": "Concentration P I (source P_i). Maps to source symbol `P_i`. Units: millimolar. Naming evidence: amount concentration units identify a concentration state."
      },
      {
        "name": "model_parameter_t_h",
        "label": "Model Parameter T H (source T_H)",
        "maps_to": "physiology_cellml_serca_threestate_b0d_model.model_parameter_t_h",
        "description": "Model Parameter T H (source T_H). Maps to source symbol `T_H`. Units: dimensionless. Naming evidence: source symbol is dimensionless but lacks enough evidence for a biological label."
      }
    ]
  },
  "title": "Physiome b0d - Serca Three State Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_serca_threestate_b0d_model",
      "alias": "physiology_cellml_serca_threestate_b0d_model",
      "parameters": {
        "model_path": "data/SERCA_ThreeState.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_serca_threestate_b0d_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_serca_threestate_b0d_model_state"
      ],
      "from": "physiology_cellml_serca_threestate_b0d_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_serca_threestate_b0d_model_summary"
      ],
      "from": "physiology_cellml_serca_threestate_b0d_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_serca_threestate_b0d_model_trajectory"
      ],
      "from": "physiology_cellml_serca_threestate_b0d_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_serca_threestate_b0d_model_variable_labels"
      ],
      "from": "physiology_cellml_serca_threestate_b0d_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for SERCA_ThreeState. Public controls and outputs are mapped to real source symbols for calcium handling.",
  "schema_version": "2.0"
}

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