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Pomerening2005- Model of the Xenopus Cdc2/APC System Lab

About lab

Single-model lab wrapper for Pomerening2005- Model of the Xenopus Cdc2/APC System. The cell-cycle oscillator includes an essential negative-feedback loop: Cdc2 activates the anaphase-promoting complex (APC), which leads to cyclin destruction and Cdc2 inactivation. It can be used to explore cell-cycle regulation dynamics and compare checkpoint behavior across conditions.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagepomerening2005-model-of-the-xenopus-cdc2-apc-system-lab
Created2026-05-15
Updated2026-05-15
cellcyclesbmlbiomodels_ebifaithfulvisualisation

Manifest

{
  "io": {
    "inputs": [],
    "outputs": [
      {
        "name": "cyclin_pool",
        "label": "Cyclin pool",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cyclin_pool",
        "description": "Tracks Cyclin pool in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cyclin_pool`."
      },
      {
        "name": "cdc2cyclin",
        "label": "Cdc2cyclin",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2cyclin",
        "description": "Tracks Cdc2cyclin in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2cyclin`."
      },
      {
        "name": "cdc2cyclinyp",
        "label": "Cdc2cyclinyp",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2cyclinyp",
        "description": "Tracks Cdc2cyclinyp in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2cyclinyp`."
      },
      {
        "name": "cdc2cyclinyptp",
        "label": "Cdc2cyclinyptp",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2cyclinyptp",
        "description": "Tracks Cdc2cyclinyptp in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2cyclinyptp`."
      },
      {
        "name": "cdc2cyclintp",
        "label": "Cdc2cyclintp",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2cyclintp",
        "description": "Tracks Cdc2cyclintp in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2cyclintp`."
      },
      {
        "name": "cdc2",
        "label": "Cdc2",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2",
        "description": "Tracks Cdc2 in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2`."
      },
      {
        "name": "cdc2afcyclin",
        "label": "Cdc2afcyclin",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2afcyclin",
        "description": "Tracks Cdc2afcyclin in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2afcyclin`."
      },
      {
        "name": "cdc2afcyclintp",
        "label": "Cdc2afcyclintp",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2afcyclintp",
        "description": "Tracks Cdc2afcyclintp in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2afcyclintp`."
      },
      {
        "name": "cdc2af",
        "label": "Cdc2af",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2af",
        "description": "Tracks Cdc2af in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc2af`."
      },
      {
        "name": "cdc25act",
        "label": "Cdc25act",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc25act",
        "description": "Tracks Cdc25act in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.cdc25act`."
      },
      {
        "name": "wee1act",
        "label": "Wee1act",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.wee1act",
        "description": "Tracks Wee1act in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.wee1act`."
      },
      {
        "name": "plxact",
        "label": "Plxact",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.plxact",
        "description": "Tracks Plxact in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.plxact`."
      },
      {
        "name": "apcstar",
        "label": "Apcstar",
        "maps_to": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.apcstar",
        "description": "Tracks Apcstar in the lab model via `cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.apcstar`."
      }
    ]
  },
  "title": "Pomerening2005- Model of the Xenopus Cdc2/APC System Lab",
  "models": [
    {
      "path": "owned/models/cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model",
      "alias": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model",
      "provenance": {
        "owned_path": "owned/models/cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model_state"
      ],
      "from": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.state"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model_summary"
      ],
      "from": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.summary"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model_species_labels"
      ],
      "from": "cellcycle_sbml_pomerening2005_model_of_the_xenopus_cdc2_apc_sys_model2005150001_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "Single-model lab wrapper for Pomerening2005- Model of the Xenopus Cdc2/APC System. The cell-cycle oscillator includes an essential negative-feedback loop: Cdc2 activates the anaphase-promoting complex (APC), which leads to cyclin destruction and Cdc2 inactivation. It can be used to explore cell-cycle regulation dynamics and compare checkpoint behavior across conditions.",
  "schema_version": "2.0"
}

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