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Boer1985 - Macrophage T cell interaction in anti-tumor response Lab

About lab

In this paper we present a model of the macrophageT lymphocyte interactions that generate ananti-tumor immune response. The modseple cifies i)induction of cytotoxic T lymphocytes, ii) antigenpresentat.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packageboer1985-macrophage-t-cell-interaction-in-anti-tumor-response-la
Created2026-05-15
Updated2026-05-15
immunologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_tumor",
        "label": "Initial Tumor",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.initial_tumor",
        "description": "Initial Tumor. Sets the initial value of bundled SBML species `Tumor`."
      },
      {
        "name": "initial_cytotoxic_t_lymphocyte_precursors",
        "label": "Initial Cytotoxic T Lymphocyte Precursors",
        "units": "native source value",
        "default": 25,
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.initial_cytotoxic_t_lymphocyte_precursors",
        "description": "Initial Cytotoxic T Lymphocyte Precursors. Sets the initial value of bundled SBML species `CTLP`."
      },
      {
        "name": "initial_cytotoxic_t_lymphocytes",
        "label": "Initial Cytotoxic T Lymphocytes",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.initial_cytotoxic_t_lymphocytes",
        "description": "Initial Cytotoxic T Lymphocytes. Sets the initial value of bundled SBML species `CTL`."
      },
      {
        "name": "initial_helper_t_lymphocyte_precursors",
        "label": "Initial Helper T Lymphocyte Precursors",
        "units": "native source value",
        "default": 15,
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.initial_helper_t_lymphocyte_precursors",
        "description": "Initial Helper T Lymphocyte Precursors. Sets the initial value of bundled SBML species `HTLP`."
      },
      {
        "name": "initial_helper_t_lymphocytes",
        "label": "Initial Helper T Lymphocytes",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.initial_helper_t_lymphocytes",
        "description": "Initial Helper T Lymphocytes. Sets the initial value of bundled SBML species `HTL`."
      },
      {
        "name": "kill_parameter",
        "label": "Kill Parameter",
        "units": "native source value",
        "default": 10,
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.kill_parameter",
        "description": "Kill Parameter. Sets bundled SBML parameter `Kill`."
      }
    ],
    "outputs": [
      {
        "name": "tumor",
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.tumor"
      },
      {
        "name": "cytotoxic_t_lymphocyte_precursors",
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.cytotoxic_t_lymphocyte_precursors"
      },
      {
        "name": "cytotoxic_t_lymphocytes",
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.cytotoxic_t_lymphocytes"
      },
      {
        "name": "helper_t_lymphocyte_precursors",
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.helper_t_lymphocyte_precursors"
      },
      {
        "name": "helper_t_lymphocytes",
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.helper_t_lymphocytes"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.species_labels"
      }
    ]
  },
  "title": "Boer1985 - Macrophage T cell interaction in anti-tumor response Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model",
      "alias": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model_state"
      ],
      "from": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model_summary"
      ],
      "from": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model_species_labels"
      ],
      "from": "immunology_sbml_boer1985_macrophage_t_cell_interaction_in_anti_t_model1911130003_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "In this paper we present a model of the macrophageT lymphocyte interactions that generate ananti-tumor immune response. The modseple cifies i)induction of cytotoxic T lymphocytes, ii) antigenpresentat.",
  "schema_version": "2.0"
}

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