Phillips2008 Ascendingarousalsystem Baseline Lab

About lab

Phillips2008 Ascendingarousalsystem Baseline

This Biosimulant lab wraps Phillips2008 Ascendingarousalsystem Baseline as a runnable systems biology model with a companion visualization module. This a model from the article: Sleep deprivation in a quantitative physiologically based model of the ascendingarousal system. It can be used to explore the configured dynamics and compare scenario outcomes across configurations.

What You'll See

The lab asks: Which source-defined system states dominate this SBML model trajectory? Source model: Phillips2008_AscendingArousalSystem_Baseline. It runs for 1.0 time units with a communication step of 0.1. The run uses the model defaults declared by the curated SBML wrapper. The generated visualizations focus on Vv, Vm, and H, combining trajectory, endpoint-comparison, and summary-table views from one completed dark-mode run.

In this captured run, Vm moved from 0 to -8.934 across 1.0 simulation windows.

Output Visualizations

Phillips2008 Ascendingarousalsystem Baseline - run interpretation

Summary table for Phillips2008 Ascendingarousalsystem Baseline, reporting the scientific question, observed answer, dominant module, and caveat.

Phillips2008 Ascendingarousalsystem Baseline - timeseries visualization

Trajectories of Vm, Vv, and H across the 1.0 simulation. In this run Vv climbed from -6.000 to 1.310 and Vm fell from 0 to -8.934 — the largest movements among the focused observables.

Phillips2008 Ascendingarousalsystem Baseline - excursions bar

Largest-excursion ranking of the focused observables — the absolute movement magnitude during the run. Top 3: Vm = 8.934, Vv = 7.310, H = 1.037.

Phillips2008 Ascendingarousalsystem Baseline - endpoint snapshot bar

Endpoint snapshot of the focused observables — final values from the captured run. Top 3 by value: H = 13.963, Vm = 8.934, Vv = 1.310.

Phillips2008 Ascendingarousalsystem Baseline - visualization

Visualization card from the Phillips2008 Ascendingarousalsystem Baseline dark-mode run.

Model Context

Core model: models/core
Visualization model: models/visualisation
Standard: other
Upstream source: biomodels_ebi:MODEL1006230110
License: CC0

Inputs

Input	Maps To	Notes
Initial Model State Vv	`systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.initial_model_state_vv`	Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Vv`.
Initial Model State Vm	`systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.initial_model_state_vm`	Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Vm`.
Initial Model State H	`systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.initial_model_state_h`	Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `H`.

Outputs

Output	Maps To	Role
`state`	`systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.state`	Available to the visualization model and downstream workflows.
`summary`	`systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.summary`	Available to the visualization model and downstream workflows.
`species_labels`	`systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.species_labels`	Available to the visualization model and downstream workflows.
`model_state_vv`	`systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.model_state_vv`	Available to the visualization model and downstream workflows.
`model_state_vm`	`systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.model_state_vm`	Available to the visualization model and downstream workflows.
`model_state_h`	`systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.model_state_h`	Available to the visualization model and downstream workflows.

Runtime

Duration: 1.0
Communication step: 0.1

Running Locally

biosimulant labs serve

This a model from the article: Sleep deprivation in a quantitative physiologically based model of the ascendingarousal system. It can be used to explore systemsbiology phillips2008 ascendingarousalsystem baseline model1006230110 dynamics and compare simulation behavior across conditions.

Runtime

Duration1

Comms Step0.1

Runs

Total0

Completed0

Failed0

Metadata

Packagephillips2008-ascendingarousalsystem-baseline-lab

Created2026-05-17

Updated2026-05-17

systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_model_state_vv",
        "label": "Initial Model State Vv",
        "maps_to": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.initial_model_state_vv",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Vv`."
      },
      {
        "name": "initial_model_state_vm",
        "label": "Initial Model State Vm",
        "maps_to": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.initial_model_state_vm",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Vm`."
      },
      {
        "name": "initial_model_state_h",
        "label": "Initial Model State H",
        "maps_to": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.initial_model_state_h",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `H`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.species_labels"
      },
      {
        "name": "model_state_vv",
        "maps_to": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.model_state_vv"
      },
      {
        "name": "model_state_vm",
        "maps_to": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.model_state_vm"
      },
      {
        "name": "model_state_h",
        "maps_to": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.model_state_h"
      }
    ]
  },
  "tags": [
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Phillips2008 Ascendingarousalsystem Baseline Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model",
      "alias": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model_state"
      ],
      "from": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model_summary"
      ],
      "from": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model_species_labels"
      ],
      "from": "systemsbiology_sbml_phillips2008_ascendingarousalsystem_baseline_model1006230110_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "This a model from the article: Sleep deprivation in a quantitative physiologically based model of the ascendingarousal system. It can be used to explore systemsbiology phillips2008 ascendingarousalsystem baseline model1006230110 dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

Select a run from History to view its results.