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Bajzer2008 - Modeling of cancer virotherapy with recombinant measles viruses Lab

About lab

This model describes the interactions between tumor cells and virus particles, with particular reference to virus-induced syncytium formation and ultimately death of tumor cells. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagebajzer2008-modeling-of-cancer-virotherapy-with-recombinant-measl
Created2026-05-16
Updated2026-05-16
biomodels_ebicurateddrug-responsefaithfulimmunotherapyoncologypharmacologyphysiologysbmlsystemsbiologytumor-growthvirotherapyvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "epsilon_source_parameter",
        "label": "Epsilon source parameter",
        "units": "native SBML value",
        "default": 1.648773,
        "maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.epsilon_source_parameter",
        "description": "Epsilon source parameter. Maps to bundled SBML parameter `epsilon`."
      },
      {
        "name": "initial_y_tumor_cell",
        "label": "Y Tumor Cell",
        "units": "native SBML value",
        "default": 126.237,
        "maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.initial_y_tumor_cell",
        "description": "Initial Y Tumor Cell. Sets the initial value of bundled SBML symbol `y_Tumor_Cell`."
      },
      {
        "name": "initial_x_infected_cell",
        "label": "X Infected Cell",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.initial_x_infected_cell",
        "description": "Initial X Infected Cell. Sets the initial value of bundled SBML symbol `x_Infected_Cell`."
      },
      {
        "name": "initial_v_virus",
        "label": "V Virus",
        "units": "native SBML value",
        "default": 2,
        "maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.initial_v_virus",
        "description": "Initial V Virus. Sets the initial value of bundled SBML symbol `v_Virus`."
      }
    ],
    "outputs": [
      {
        "name": "y_tumor_cell",
        "maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.y_tumor_cell",
        "description": "Y Tumor Cell observable. Maps to SBML symbol `y_Tumor_Cell`."
      },
      {
        "name": "x_infected_cell",
        "maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.x_infected_cell",
        "description": "X Infected Cell observable. Maps to SBML symbol `x_Infected_Cell`."
      },
      {
        "name": "v_virus",
        "maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.v_virus",
        "description": "V Virus observable. Maps to SBML symbol `v_Virus`."
      },
      {
        "name": "state",
        "maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.state",
        "description": "Full raw SBML observable record for reproducibility and downstream visualisation."
      },
      {
        "name": "summary",
        "maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.summary",
        "description": "Change and peak summary across the simulated SBML observables."
      },
      {
        "name": "species_labels",
        "maps_to": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.species_labels",
        "description": "Mapping from selected raw SBML observable symbols to display labels."
      }
    ]
  },
  "tags": [
    "biomodels_ebi",
    "curated",
    "drug-response",
    "faithful",
    "immunotherapy",
    "oncology",
    "pharmacology",
    "physiology",
    "sbml",
    "systemsbiology",
    "tumor-growth",
    "virotherapy"
  ],
  "title": "Bajzer2008 - Modeling of cancer virotherapy with recombinant measles viruses Lab",
  "models": [
    {
      "path": "owned/models/oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model",
      "alias": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model",
      "provenance": {
        "owned_path": "owned/models/oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model_state"
      ],
      "from": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.state"
    },
    {
      "to": [
        "visualisation.oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model_summary"
      ],
      "from": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.summary"
    },
    {
      "to": [
        "visualisation.oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model_species_labels"
      ],
      "from": "oncology_sbml_bajzer2008_modeling_of_cancer_virotherapy_with_r_biomd0000000771_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This model describes the interactions between tumor cells and virus particles, with particular reference to virus-induced syncytium formation and ultimately death of tumor cells. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.",
  "schema_version": "2.0"
}

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