Fribourg2014 - Model of influenza A virus infection dynamics of viral antagonism and innate immune response. Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_interferon_beta_mrna",
        "label": "Initial Interferon Beta mRNA",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.initial_interferon_beta_mrna",
        "description": "Initial Interferon Beta mRNA. Sets the initial value of bundled SBML species `IFNBm`."
      },
      {
        "name": "initial_extracellular_interferon_beta",
        "label": "Initial Extracellular Interferon Beta",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.initial_extracellular_interferon_beta",
        "description": "Initial Extracellular Interferon Beta. Sets the initial value of bundled SBML species `IFNBenv`."
      },
      {
        "name": "initial_interferon_alpha_mrna",
        "label": "Initial Interferon Alpha mRNA",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.initial_interferon_alpha_mrna",
        "description": "Initial Interferon Alpha mRNA. Sets the initial value of bundled SBML species `IFNam`."
      },
      {
        "name": "initial_extracellular_interferon_alpha",
        "label": "Initial Extracellular Interferon Alpha",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.initial_extracellular_interferon_alpha",
        "description": "Initial Extracellular Interferon Alpha. Sets the initial value of bundled SBML species `IFNaenv`."
      },
      {
        "name": "initial_nuclear_phosphorylated_stat2",
        "label": "Initial Nuclear Phosphorylated Stat2",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.initial_nuclear_phosphorylated_stat2",
        "description": "Initial Nuclear Phosphorylated Stat2. Sets the initial value of bundled SBML species `STATP2n`."
      }
    ],
    "outputs": [
      {
        "name": "interferon_beta_mrna",
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.interferon_beta_mrna"
      },
      {
        "name": "extracellular_interferon_beta",
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.extracellular_interferon_beta"
      },
      {
        "name": "interferon_alpha_mrna",
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.interferon_alpha_mrna"
      },
      {
        "name": "extracellular_interferon_alpha",
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.extracellular_interferon_alpha"
      },
      {
        "name": "nuclear_phosphorylated_stat2",
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.nuclear_phosphorylated_stat2"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.species_labels"
      }
    ]
  },
  "title": "Fribourg2014 - Model of influenza A virus infection dynamics of viral antagonism and innate immune response. Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model",
      "alias": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model_state"
      ],
      "from": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model_summary"
      ],
      "from": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model_species_labels"
      ],
      "from": "immunology_sbml_fribourg2014_model_of_influenza_a_virus_infectio_biomd0000000889_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This is an ordinary differential equation mathematical model investigating the early responses of human monocyte-derived dendritic cells to infection by two H1N1 influenza A viruses of different clini. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}