Chen2006 - Popel Mathematical Biochemical Pathways Nitric Oxide Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_citrulline",
        "label": "Initial Citrulline",
        "maps_to": "physiology_cellml_chen_popel_2006_36b_model.initial_citrulline",
        "description": "Initial value for Citrulline. Maps to source symbol `citrulline`. Units: micromolar. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "micromolar"
        ]
      },
      {
        "name": "initial_hydroxyl_l_arginine",
        "label": "Initial Hydroxyl L Arginine",
        "maps_to": "physiology_cellml_chen_popel_2006_36b_model.initial_hydroxyl_l_arginine",
        "description": "Initial value for Hydroxyl L Arginine. Maps to source symbol `NOHA`. Units: micromolar. Naming evidence: source metadata names `NOHA` as `hydroxyl-L-arginine`.",
        "accepted_units": [
          "micromolar"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_chen_popel_2006_36b_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_chen_popel_2006_36b_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_chen_popel_2006_36b_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_chen_popel_2006_36b_model.variable_labels"
      },
      {
        "name": "oxygen",
        "label": "Oxygen",
        "maps_to": "physiology_cellml_chen_popel_2006_36b_model.oxygen",
        "description": "Oxygen. Maps to source symbol `O2`. Units: micromolar. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "citrulline",
        "label": "Citrulline",
        "maps_to": "physiology_cellml_chen_popel_2006_36b_model.citrulline",
        "description": "Citrulline. Maps to source symbol `citrulline`. Units: micromolar. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "neuronal_nitric_oxide_synthase_heme_iron_2plus",
        "label": "Neuronal Nitric Oxide Synthase Heme Iron 2plus",
        "maps_to": "physiology_cellml_chen_popel_2006_36b_model.neuronal_nitric_oxide_synthase_heme_iron_2plus",
        "description": "Neuronal Nitric Oxide Synthase Heme Iron 2plus. Maps to source symbol `Fe2`. Units: micromolar. Naming evidence: source metadata names `Fe2` as `neuronal nitric oxide synthase (heme iron 2+)`."
      },
      {
        "name": "neuronal_nitric_oxide_synthase_heme_iron_2plus_bound_to_l_argini",
        "label": "Neuronal Nitric Oxide Synthase Heme Iron 2plus Bound To L Argini",
        "maps_to": "physiology_cellml_chen_popel_2006_36b_model.neuronal_nitric_oxide_synthase_heme_iron_2plus_bound_to_l_argini",
        "description": "Neuronal Nitric Oxide Synthase Heme Iron 2plus Bound To L Argini. Maps to source symbol `Fe2_Arg`. Units: micromolar. Naming evidence: source metadata names `Fe2_Arg` as `neuronal nitric oxide synthase (heme iron 2+) bound to L-arginine`."
      },
      {
        "name": "neuronal_nitric_oxide_synthase_heme_iron_2plus_bound_to_nitric_o",
        "label": "Neuronal Nitric Oxide Synthase Heme Iron 2plus Bound To Nitric O",
        "maps_to": "physiology_cellml_chen_popel_2006_36b_model.neuronal_nitric_oxide_synthase_heme_iron_2plus_bound_to_nitric_o",
        "description": "Neuronal Nitric Oxide Synthase Heme Iron 2plus Bound To Nitric O. Maps to source symbol `Fe2_NO`. Units: micromolar. Naming evidence: source metadata names `Fe2_NO` as `neuronal nitric oxide synthase (heme iron 2+) bound to nitric oxide`."
      },
      {
        "name": "l_arginine",
        "label": "L Arginine",
        "maps_to": "physiology_cellml_chen_popel_2006_36b_model.l_arginine",
        "description": "L Arginine. Maps to source symbol `Arg`. Units: micromolar. Naming evidence: source metadata names `Arg` as `L-arginine`."
      }
    ]
  },
  "title": "Chen2006 - Popel Mathematical Biochemical Pathways Nitric Oxide Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "physiology_cellml_chen_popel_2006_36b_model",
      "parameters": {
        "model_path": "data/chen_popel_2006.cellml",
        "integration_step": 0.01
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_chen_popel_2006_36b_model_state"
      ],
      "from": "physiology_cellml_chen_popel_2006_36b_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_chen_popel_2006_36b_model_summary"
      ],
      "from": "physiology_cellml_chen_popel_2006_36b_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_chen_popel_2006_36b_model_trajectory"
      ],
      "from": "physiology_cellml_chen_popel_2006_36b_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_chen_popel_2006_36b_model_variable_labels"
      ],
      "from": "physiology_cellml_chen_popel_2006_36b_model.variable_labels"
    }
  ],
  "package": "chen2006-popel-mathematical-biochemical-pathways-nitric-oxide",
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "version": "1.0.0",
  "description": "Source-faithful physiology lab for Chen, Popel, 2006. Public controls and outputs are mapped to real source symbols for source-model physiology.",
  "schema_version": "2.0"
}