Ganguli2018-immuno regulatory mechanisms in tumor microenvironment Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_cancer_stem_cells_s",
        "label": "Initial Cancer Stem Cells S",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.initial_cancer_stem_cells_s",
        "description": "Initial Cancer Stem Cells S. Sets the initial value of bundled SBML species `Cancer_Stem_Cells_S`."
      },
      {
        "name": "initial_cancer_cells_c",
        "label": "Initial Cancer Cells C",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.initial_cancer_cells_c",
        "description": "Initial Cancer Cells C. Sets the initial value of bundled SBML species `Cancer_Cells_C`."
      },
      {
        "name": "initial_resistant_cancer_cells_c_r",
        "label": "Initial Resistant Cancer Cells C R",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.initial_resistant_cancer_cells_c_r",
        "description": "Initial Resistant Cancer Cells C R. Sets the initial value of bundled SBML species `Resistant_Cancer_Cells_C_R`."
      },
      {
        "name": "initial_unresolved_tumor_observable_1",
        "label": "Initial Unresolved Tumor Observable 1",
        "units": "native source value",
        "default": 85000,
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.initial_unresolved_tumor_observable_1",
        "description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `M1_Tumor_Associated_Macrophages`."
      },
      {
        "name": "initial_unresolved_tumor_observable_2",
        "label": "Initial Unresolved Tumor Observable 2",
        "units": "native source value",
        "default": 15000,
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.initial_unresolved_tumor_observable_2",
        "description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `M2_Tumor_Associated_Macrophages`."
      },
      {
        "name": "gompertzian_growth_of_cancer_cells_c_rate",
        "label": "Gompertzian Growth Of Cancer Cells C Rate",
        "units": "native source value",
        "default": 0.0001,
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.gompertzian_growth_of_cancer_cells_c_rate",
        "description": "Gompertzian Growth Of Cancer Cells C Rate. Sets bundled SBML parameter `r_1`."
      },
      {
        "name": "gompertzian_growth_of_resistant_cancer_cells_cr_rate",
        "label": "Gompertzian Growth Of Resistant Cancer Cells Cr Rate",
        "units": "native source value",
        "default": 0.00001,
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.gompertzian_growth_of_resistant_cancer_cells_cr_rate",
        "description": "Gompertzian Growth Of Resistant Cancer Cells Cr Rate. Sets bundled SBML parameter `r_2`."
      },
      {
        "name": "proliferation_on_cancer_cells_c_interleukin_10_rate",
        "label": "Proliferation On Cancer Cells C Interleukin 10 Rate",
        "units": "unit_2",
        "default": 2.0531,
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.proliferation_on_cancer_cells_c_interleukin_10_rate",
        "description": "Proliferation On Cancer Cells C Interleukin 10 Rate. Sets bundled SBML parameter `k3`."
      },
      {
        "name": "proliferation_on_resistant_cancer_cells_cr_interleukin_10_rate",
        "label": "Proliferation On Resistant Cancer Cells Cr Interleukin 10 Rate",
        "units": "unit_2",
        "default": 6.7979,
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.proliferation_on_resistant_cancer_cells_cr_interleukin_10_rate",
        "description": "Proliferation On Resistant Cancer Cells Cr Interleukin 10 Rate. Sets bundled SBML parameter `k5`."
      }
    ],
    "outputs": [
      {
        "name": "cancer_stem_cells_s",
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.cancer_stem_cells_s"
      },
      {
        "name": "cancer_cells_c",
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.cancer_cells_c"
      },
      {
        "name": "resistant_cancer_cells_c_r",
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.resistant_cancer_cells_c_r"
      },
      {
        "name": "unresolved_tumor_observable_1",
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.unresolved_tumor_observable_1"
      },
      {
        "name": "unresolved_tumor_observable_2",
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.unresolved_tumor_observable_2"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.species_labels"
      }
    ]
  },
  "title": "Ganguli2018-immuno regulatory mechanisms in tumor microenvironment Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model",
      "alias": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model_state"
      ],
      "from": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model_summary"
      ],
      "from": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model_species_labels"
      ],
      "from": "immunology_sbml_ganguli2018_immuno_regulatory_mechanisms_in_tumo_biomd0000000810_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This model describes the concept of Cancer Stem Cells(CSC) differentiation and tumor-immune interaction into a generic model that has been validated with known experimental data. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}