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den Breems2015 - macrophage in cancer Lab

About lab

The paper describes a model of re-polarisation of M2 and M1 macrophages and its role on cancer outcomes. Created by COPASI 4.25 (Build 207) This model is described in the article: The re-polarisation.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packageden-breems2015-macrophage-in-cancer-lab
Created2026-05-15
Updated2026-05-15
immunologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_unresolved_tumor_observable_1",
        "label": "Initial Unresolved Tumor Observable 1",
        "units": "native source value",
        "default": 1000,
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.initial_unresolved_tumor_observable_1",
        "description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `Tn`."
      },
      {
        "name": "initial_unresolved_tumor_observable_2",
        "label": "Initial Unresolved Tumor Observable 2",
        "units": "native source value",
        "default": 1000000,
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.initial_unresolved_tumor_observable_2",
        "description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `Ts`."
      },
      {
        "name": "initial_unresolved_tumor_observable_3",
        "label": "Initial Unresolved Tumor Observable 3",
        "units": "native source value",
        "default": 100,
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.initial_unresolved_tumor_observable_3",
        "description": "Initial Unresolved Tumor Observable 3. Sets the initial value of bundled SBML species `M1`."
      },
      {
        "name": "initial_unresolved_tumor_observable_4",
        "label": "Initial Unresolved Tumor Observable 4",
        "units": "native source value",
        "default": 100,
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.initial_unresolved_tumor_observable_4",
        "description": "Initial Unresolved Tumor Observable 4. Sets the initial value of bundled SBML species `M2`."
      },
      {
        "name": "initial_unresolved_tumor_observable_5",
        "label": "Initial Unresolved Tumor Observable 5",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.initial_unresolved_tumor_observable_5",
        "description": "Initial Unresolved Tumor Observable 5. Sets the initial value of bundled SBML species `Th1`."
      }
    ],
    "outputs": [
      {
        "name": "unresolved_tumor_observable_1",
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.unresolved_tumor_observable_1"
      },
      {
        "name": "unresolved_tumor_observable_2",
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.unresolved_tumor_observable_2"
      },
      {
        "name": "unresolved_tumor_observable_3",
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.unresolved_tumor_observable_3"
      },
      {
        "name": "unresolved_tumor_observable_4",
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.unresolved_tumor_observable_4"
      },
      {
        "name": "unresolved_tumor_observable_5",
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.unresolved_tumor_observable_5"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.species_labels"
      }
    ]
  },
  "title": "den Breems2015 - macrophage in cancer Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model",
      "alias": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model_state"
      ],
      "from": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model_summary"
      ],
      "from": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model_species_labels"
      ],
      "from": "immunology_sbml_den_breems2015_macrophage_in_cancer_biomd0000000759_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "The paper describes a model of re-polarisation of M2 and M1 macrophages and its role on cancer outcomes. Created by COPASI 4.25 (Build 207) This model is described in the article: The re-polarisation.",
  "schema_version": "2.0"
}

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