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Smith1980 - Mathematical Hypothalamic Regulation Pituitary Secretion Lab

About lab

Source-faithful physiology lab for Smith, 1980. Public controls and outputs are mapped to real source symbols for source-model physiology.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packagesmith1980-mathematical-hypothalamic-regulation-pituitary-secreti
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_lh",
        "label": "Initial Lh",
        "maps_to": "physiology_cellml_smith_1980_smith1980_model.initial_lh",
        "description": "Initial value for Lh. Maps to source symbol `L`. Units: ng_ml. Naming evidence: source metadata names `L` as `LH`.",
        "accepted_units": [
          "ng_ml"
        ]
      },
      {
        "name": "initial_lhrh",
        "label": "Initial Lhrh",
        "maps_to": "physiology_cellml_smith_1980_smith1980_model.initial_lhrh",
        "description": "Initial value for Lhrh. Maps to source symbol `R`. Units: ng_ml. Naming evidence: source metadata names `R` as `LHRH`.",
        "accepted_units": [
          "ng_ml"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_smith_1980_smith1980_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_smith_1980_smith1980_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_smith_1980_smith1980_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_smith_1980_smith1980_model.variable_labels"
      },
      {
        "name": "lh",
        "label": "Lh",
        "maps_to": "physiology_cellml_smith_1980_smith1980_model.lh",
        "description": "Lh. Maps to source symbol `L`. Units: ng_ml. Naming evidence: source metadata names `L` as `LH`."
      },
      {
        "name": "lhrh",
        "label": "Lhrh",
        "maps_to": "physiology_cellml_smith_1980_smith1980_model.lhrh",
        "description": "Lhrh. Maps to source symbol `R`. Units: ng_ml. Naming evidence: source metadata names `R` as `LHRH`."
      },
      {
        "name": "testosterone",
        "label": "Testosterone",
        "maps_to": "physiology_cellml_smith_1980_smith1980_model.testosterone",
        "description": "Testosterone. Maps to source symbol `T`. Units: ng_ml. Naming evidence: source metadata names `T` as `testosterone`."
      },
      {
        "name": "model_parameter_h",
        "label": "Model Parameter H (source H)",
        "maps_to": "physiology_cellml_smith_1980_smith1980_model.model_parameter_h",
        "description": "Model Parameter H (source H). Maps to source symbol `H`. Units: dimensionless. Naming evidence: source symbol is dimensionless but lacks enough evidence for a biological label."
      },
      {
        "name": "rate_constant_b2",
        "label": "Rate Constant B2 (source b2)",
        "maps_to": "physiology_cellml_smith_1980_smith1980_model.rate_constant_b2",
        "description": "Rate Constant B2 (source b2). Maps to source symbol `b2`. Units: first_order_rate_constant. Naming evidence: units identify a rate constant but not a fuller biological role."
      },
      {
        "name": "rate_constant_g1",
        "label": "Rate Constant G1 (source g1)",
        "maps_to": "physiology_cellml_smith_1980_smith1980_model.rate_constant_g1",
        "description": "Rate Constant G1 (source g1). Maps to source symbol `g1`. Units: first_order_rate_constant. Naming evidence: units identify a rate constant but not a fuller biological role."
      }
    ]
  },
  "title": "Smith1980 - Mathematical Hypothalamic Regulation Pituitary Secretion Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_smith_1980_smith1980_model",
      "alias": "physiology_cellml_smith_1980_smith1980_model",
      "parameters": {
        "model_path": "data/smith_1980.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_smith_1980_smith1980_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_smith_1980_smith1980_model_state"
      ],
      "from": "physiology_cellml_smith_1980_smith1980_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_smith_1980_smith1980_model_summary"
      ],
      "from": "physiology_cellml_smith_1980_smith1980_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_smith_1980_smith1980_model_trajectory"
      ],
      "from": "physiology_cellml_smith_1980_smith1980_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_smith_1980_smith1980_model_variable_labels"
      ],
      "from": "physiology_cellml_smith_1980_smith1980_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Smith, 1980. Public controls and outputs are mapped to real source symbols for source-model physiology.",
  "schema_version": "2.0"
}

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