Perez-Garcia19 - Computational design of improved standardized chemotherapy protocols for grade 2 oligodendrogliomas Lab

{
  "io": {
    "inputs": [
      {
        "name": "dose_5_source_parameter",
        "label": "Dose 5 source parameter",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.dose_5_source_parameter",
        "description": "Dose 5 source parameter. Maps to bundled SBML parameter `dose_5`."
      },
      {
        "name": "dose_4_source_parameter",
        "label": "Dose 4 source parameter",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.dose_4_source_parameter",
        "description": "Dose 4 source parameter. Maps to bundled SBML parameter `dose_4`."
      },
      {
        "name": "dose3_source_parameter",
        "label": "Dose3 source parameter",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.dose3_source_parameter",
        "description": "Dose3 source parameter. Maps to bundled SBML parameter `dose3`."
      },
      {
        "name": "dose2_source_parameter",
        "label": "Dose2 source parameter",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.dose2_source_parameter",
        "description": "Dose2 source parameter. Maps to bundled SBML parameter `dose2`."
      },
      {
        "name": "initial_damaged_tumor_cells_d",
        "label": "Damaged Tumor Cells D",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.initial_damaged_tumor_cells_d",
        "description": "Initial Damaged Tumor Cells D. Sets the initial value of bundled SBML symbol `Damaged_Tumor_Cells_D`."
      },
      {
        "name": "initial_tumor_cell_population_p",
        "label": "Tumor Cell Population P",
        "units": "native SBML value",
        "default": 144.952075141053,
        "maps_to": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.initial_tumor_cell_population_p",
        "description": "Initial Tumor Cell Population P. Sets the initial value of bundled SBML symbol `Tumor_Cell_Population_P`."
      }
    ],
    "outputs": [
      {
        "name": "damaged_tumor_cells_d",
        "maps_to": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.damaged_tumor_cells_d",
        "description": "Damaged Tumor Cells D observable. Maps to SBML symbol `Damaged_Tumor_Cells_D`."
      },
      {
        "name": "tumor_cell_population_p",
        "maps_to": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.tumor_cell_population_p",
        "description": "Tumor Cell Population P observable. Maps to SBML symbol `Tumor_Cell_Population_P`."
      },
      {
        "name": "drug_concentration_c",
        "maps_to": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.drug_concentration_c",
        "description": "Drug Concentration C observable. Maps to SBML symbol `Drug_Concentration_C`."
      },
      {
        "name": "state",
        "maps_to": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.state",
        "description": "Full raw SBML observable record for reproducibility and downstream visualisation."
      },
      {
        "name": "summary",
        "maps_to": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.summary",
        "description": "Change and peak summary across the simulated SBML observables."
      },
      {
        "name": "species_labels",
        "maps_to": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.species_labels",
        "description": "Mapping from selected raw SBML observable symbols to display labels."
      }
    ]
  },
  "tags": [
    "biomodels_ebi",
    "chemotherapy",
    "curated",
    "drug-response",
    "faithful",
    "oncology",
    "pharmacology",
    "physiology",
    "sbml",
    "systemsbiology",
    "tumor-growth"
  ],
  "title": "Perez-Garcia19 - Computational design of improved standardized chemotherapy protocols for grade 2 oligodendrogliomas Lab",
  "models": [
    {
      "path": "owned/models/oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model",
      "alias": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model",
      "provenance": {
        "owned_path": "owned/models/oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model_state"
      ],
      "from": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.state"
    },
    {
      "to": [
        "visualisation.oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model_summary"
      ],
      "from": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.summary"
    },
    {
      "to": [
        "visualisation.oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model_species_labels"
      ],
      "from": "oncology_sbml_perez_garcia19_computational_design_of_improved_biomd0000000814_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This is a model built by COPASI4.24(Build 197)This a model from the article: Computational design of improved standardized chemotherapy protocols for grade II oligodendrogliomasVíctor M. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.",
  "schema_version": "2.0"
}