About lab
This is a reinvestigation of a previous model depicting cancer remission. It involves application of mathematical tools from control theory to assess the optimal approach during the use of Adaptive Ce.
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Duration10
Comms Step1
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Metadata
Packagechakrabarty2010-a-control-theory-approach-to-cancer-rem-08a146de
Created2026-05-16
Updated2026-06-13
biomodels_ebicurateddrug-responsefaithfuloncologypharmacologyphysiologysbmlsystemsbiologytumor-growthvisualisationother
Manifest
{
"io": {
"inputs": [
{
"name": "initial_m_tumor_cells",
"label": "M Tumor Cells",
"units": "native SBML value",
"default": 2750000,
"maps_to": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model.initial_m_tumor_cells",
"description": "Initial M Tumor Cells. Sets the initial value of bundled SBML symbol `M_Tumor_Cells`."
},
{
"name": "initial_n_ctl",
"label": "N CTL",
"units": "native SBML value",
"default": 200000,
"maps_to": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model.initial_n_ctl",
"description": "Initial N CTL. Sets the initial value of bundled SBML symbol `N_CTL`."
},
{
"name": "initial_z_thl",
"label": "Z THL",
"units": "native SBML value",
"default": 7200000,
"maps_to": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model.initial_z_thl",
"description": "Initial Z THL. Sets the initial value of bundled SBML symbol `Z_THL`."
}
],
"outputs": [
{
"name": "m_tumor_cells",
"maps_to": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model.m_tumor_cells",
"description": "M Tumor Cells observable. Maps to SBML symbol `M_Tumor_Cells`."
},
{
"name": "n_ctl",
"maps_to": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model.n_ctl",
"description": "N CTL observable. Maps to SBML symbol `N_CTL`."
},
{
"name": "z_thl",
"maps_to": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model.z_thl",
"description": "Z THL observable. Maps to SBML symbol `Z_THL`."
},
{
"name": "state",
"maps_to": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model.state",
"description": "Full raw SBML observable record for reproducibility and downstream visualisation."
},
{
"name": "summary",
"maps_to": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model.summary",
"description": "Change and peak summary across the simulated SBML observables."
},
{
"name": "species_labels",
"maps_to": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model.species_labels",
"description": "Mapping from selected raw SBML observable symbols to display labels."
}
]
},
"tags": [
"biomodels_ebi",
"curated",
"drug-response",
"faithful",
"oncology",
"pharmacology",
"physiology",
"sbml",
"systemsbiology",
"tumor-growth"
],
"title": "Chakrabarty2010 - A control theory approach to cancer remission aided by an optimal therapy Lab",
"models": [
{
"path": "models/core",
"alias": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model"
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model_state"
],
"from": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model.state"
},
{
"to": [
"visualisation.oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model_summary"
],
"from": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model.summary"
},
{
"to": [
"visualisation.oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model_species_labels"
],
"from": "oncology_sbml_chakrabarty2010_a_control_theory_approach_to_can_biomd0000000777_model.species_labels"
}
],
"package": "chakrabarty2010-a-control-theory-approach-to-cancer-rem-08a146de",
"runtime": {
"duration": 10,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "This is a reinvestigation of a previous model depicting cancer remission. It involves application of mathematical tools from control theory to assess the optimal approach during the use of Adaptive Ce.",
"schema_version": "2.0"
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