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Hai1988 - Cross Bridge Phosphorylation Regulation Latch State Smooth Lab

About lab

Source-faithful physiology lab for Hai and Murphy 1988. Public controls and outputs are mapped to real source symbols for source-model physiology.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packagehai1988-cross-bridge-phosphorylation-regulation-latch-state-smoo
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_amp",
        "label": "Initial Amp",
        "maps_to": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.initial_amp",
        "description": "Initial value for Amp. Maps to source symbol `AMp`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "dimensionless"
        ]
      },
      {
        "name": "initial_attached_crossbridge_am",
        "label": "Initial Attached Crossbridge Am (source AM)",
        "maps_to": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.initial_attached_crossbridge_am",
        "description": "Initial value for Attached Crossbridge Am (source AM). Maps to source symbol `AM`. Units: dimensionless. Naming evidence: cross-bridge/latch-state model context supports a conservative cross-bridge state label.",
        "accepted_units": [
          "dimensionless"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.variable_labels"
      },
      {
        "name": "amp",
        "label": "Amp",
        "maps_to": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.amp",
        "description": "Amp. Maps to source symbol `AMp`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "attached_crossbridge_am",
        "label": "Attached Crossbridge Am (source AM)",
        "maps_to": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.attached_crossbridge_am",
        "description": "Attached Crossbridge Am (source AM). Maps to source symbol `AM`. Units: dimensionless. Naming evidence: cross-bridge/latch-state model context supports a conservative cross-bridge state label."
      },
      {
        "name": "detached_crossbridge_m",
        "label": "Detached Crossbridge M (source M)",
        "maps_to": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.detached_crossbridge_m",
        "description": "Detached Crossbridge M (source M). Maps to source symbol `M`. Units: dimensionless. Naming evidence: cross-bridge/latch-state model context supports a conservative cross-bridge state label."
      },
      {
        "name": "phosphorylated_detached_crossbridge_mp",
        "label": "Phosphorylated Detached Crossbridge Mp (source Mp)",
        "maps_to": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.phosphorylated_detached_crossbridge_mp",
        "description": "Phosphorylated Detached Crossbridge Mp (source Mp). Maps to source symbol `Mp`. Units: dimensionless. Naming evidence: cross-bridge/latch-state model context supports a conservative cross-bridge state label."
      },
      {
        "name": "model_parameters_k1",
        "label": "Model Parameters K1",
        "maps_to": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.model_parameters_k1",
        "description": "Model Parameters K1. Maps to source symbol `k1`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "model_parameters_k2",
        "label": "Model Parameters K2",
        "maps_to": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.model_parameters_k2",
        "description": "Model Parameters K2. Maps to source symbol `k2`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
      }
    ]
  },
  "title": "Hai1988 - Cross Bridge Phosphorylation Regulation Latch State Smooth Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_hai_and_murphy_1988_haimurphy1988_model",
      "alias": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model",
      "parameters": {
        "model_path": "data/hai_1988.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_hai_and_murphy_1988_haimurphy1988_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_hai_and_murphy_1988_haimurphy1988_model_state"
      ],
      "from": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_hai_and_murphy_1988_haimurphy1988_model_summary"
      ],
      "from": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_hai_and_murphy_1988_haimurphy1988_model_trajectory"
      ],
      "from": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_hai_and_murphy_1988_haimurphy1988_model_variable_labels"
      ],
      "from": "physiology_cellml_hai_and_murphy_1988_haimurphy1988_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Hai and Murphy 1988. Public controls and outputs are mapped to real source symbols for source-model physiology.",
  "schema_version": "2.0"
}

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