Fallon2000 - Lauffenburger Effects Ligand Receptor Binding Properties Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_cell_surface_il_2_il_2_r_ligand_receptor_complex_density",
        "label": "Initial Cell Surface Il 2 Il 2 R Ligand Receptor Complex Density",
        "maps_to": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.initial_cell_surface_il_2_il_2_r_ligand_receptor_complex_density",
        "description": "Initial value for Cell Surface Il 2 Il 2 R Ligand Receptor Complex Density. Maps to source symbol `Cs`. Units: number_per_cell. Naming evidence: source metadata names `Cs` as `cell surface IL-2-IL-2R (ligand-receptor complex) density`.",
        "accepted_units": [
          "number_per_cell"
        ]
      },
      {
        "name": "initial_cell_surface_il_2_receptor_density",
        "label": "Initial Cell Surface Il 2 Receptor Density",
        "maps_to": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.initial_cell_surface_il_2_receptor_density",
        "description": "Initial value for Cell Surface Il 2 Receptor Density. Maps to source symbol `Rs`. Units: number_per_cell. Naming evidence: source metadata names `Rs` as `cell surface IL-2 receptor density`.",
        "accepted_units": [
          "number_per_cell"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.variable_labels"
      },
      {
        "name": "cell_surface_il_2_il_2_r_ligand_receptor_complex_density",
        "label": "Cell Surface Il 2 Il 2 R Ligand Receptor Complex Density",
        "maps_to": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.cell_surface_il_2_il_2_r_ligand_receptor_complex_density",
        "description": "Cell Surface Il 2 Il 2 R Ligand Receptor Complex Density. Maps to source symbol `Cs`. Units: number_per_cell. Naming evidence: source metadata names `Cs` as `cell surface IL-2-IL-2R (ligand-receptor complex) density`."
      },
      {
        "name": "cell_surface_il_2_receptor_density",
        "label": "Cell Surface Il 2 Receptor Density",
        "maps_to": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.cell_surface_il_2_receptor_density",
        "description": "Cell Surface Il 2 Receptor Density. Maps to source symbol `Rs`. Units: number_per_cell. Naming evidence: source metadata names `Rs` as `cell surface IL-2 receptor density`."
      },
      {
        "name": "intracellular_il_2_il_2_r_ligand_receptor_complex_density",
        "label": "Intracellular Il 2 Il 2 R Ligand Receptor Complex Density",
        "maps_to": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.intracellular_il_2_il_2_r_ligand_receptor_complex_density",
        "description": "Intracellular Il 2 Il 2 R Ligand Receptor Complex Density. Maps to source symbol `Ci`. Units: number_per_cell. Naming evidence: source metadata names `Ci` as `intracellular IL-2-IL-2R (ligand-receptor complex) density`."
      },
      {
        "name": "intracellular_il_2_receptor_density",
        "label": "Intracellular Il 2 Receptor Density",
        "maps_to": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.intracellular_il_2_receptor_density",
        "description": "Intracellular Il 2 Receptor Density. Maps to source symbol `Ri`. Units: number_per_cell. Naming evidence: source metadata names `Ri` as `intracellular IL-2 receptor density`."
      },
      {
        "name": "cell_population_ld",
        "label": "Cell Population Ld (source Ld)",
        "maps_to": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.cell_population_ld",
        "description": "Cell Population Ld (source Ld). Maps to source symbol `Ld`. Units: number_per_cell. Naming evidence: cell units identify a cell-population state."
      },
      {
        "name": "intracellular_il_2_density",
        "label": "Intracellular Il 2 Density",
        "maps_to": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.intracellular_il_2_density",
        "description": "Intracellular Il 2 Density. Maps to source symbol `Li`. Units: picomolar. Naming evidence: source metadata names `Li` as `intracellular IL-2 density`."
      }
    ]
  },
  "title": "Fallon2000 - Lauffenburger Effects Ligand Receptor Binding Properties Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model",
      "parameters": {
        "model_path": "data/fallon_lauffenburger_2000.cellml",
        "integration_step": 0.01
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model_state"
      ],
      "from": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model_summary"
      ],
      "from": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model_trajectory"
      ],
      "from": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model_variable_labels"
      ],
      "from": "physiology_cellml_fallon_lauffenburger_2000_fallonlauffenburger2000_model.variable_labels"
    }
  ],
  "package": "fallon2000-lauffenburger-effects-ligand-receptor-bindin-8212a2f1",
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "version": "1.0.0",
  "description": "Source-faithful physiology lab for Fallon, Lauffenburger, 2000. Public controls and outputs are mapped to real source symbols for signalling physiology.",
  "schema_version": "2.0"
}