Adlung2021 - Cell-to-cell variability in JAK2/STAT5 pathway Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_epo_receptor_jak2_complex",
        "label": "Initial EPO receptor-JAK2 complex",
        "maps_to": "signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model.initial_epo_receptor_jak2_complex",
        "description": "Initial level of EPO receptor-JAK2 complex. Maps to SBML symbol `EpoRJAK2`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "stat5",
        "label": "STAT5",
        "maps_to": "signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model.stat5",
        "description": "STAT5. Maps to SBML symbol `STAT5` and is emitted in native SBML units."
      },
      {
        "name": "phosphorylated_stat5",
        "label": "phosphorylated STAT5",
        "maps_to": "signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model.phosphorylated_stat5",
        "description": "phosphorylated STAT5. Maps to SBML symbol `pSTAT5` and is emitted in native SBML units."
      },
      {
        "name": "nuclear_phosphorylated_stat5",
        "label": "nuclear phosphorylated STAT5",
        "maps_to": "signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model.nuclear_phosphorylated_stat5",
        "description": "nuclear phosphorylated STAT5. Maps to SBML symbol `npSTAT5` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "jak-stat"
  ],
  "title": "Adlung2021 - Cell-to-cell variability in JAK2/STAT5 pathway Lab",
  "models": [
    {
      "path": "owned/models/signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model",
      "alias": "signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model",
      "provenance": {
        "owned_path": "owned/models/signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model_state"
      ],
      "from": "signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model_summary"
      ],
      "from": "signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model_species_labels"
      ],
      "from": "signaling_sbml_adlung2021_cell_to_cell_variability_in_jak2_stat_biomd0000001077_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Clean Biosimulant lab for JAK/STAT cytokine signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}