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Draghi2019 - Parameter identification of a model for prostate cancer treated by intermittent therapy Lab

About lab

This is a mathematical describing the interaction between the prostate adenocarcinoma tumor environment, the prostate specific antigen (PSA) produced by hormone-dependent and hormone-independent tumor. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagedraghi2019-parameter-identification-of-a-model-for-prostate-canc
Created2026-05-15
Updated2026-05-15
immunologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_unresolved_tumor_observable_1",
        "label": "Initial Unresolved Tumor Observable 1",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.initial_unresolved_tumor_observable_1",
        "description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `p`."
      },
      {
        "name": "initial_unresolved_tumor_observable_2",
        "label": "Initial Unresolved Tumor Observable 2",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.initial_unresolved_tumor_observable_2",
        "description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `a`."
      },
      {
        "name": "initial_unresolved_tumor_observable_3",
        "label": "Initial Unresolved Tumor Observable 3",
        "units": "native source value",
        "default": 0.1,
        "maps_to": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.initial_unresolved_tumor_observable_3",
        "description": "Initial Unresolved Tumor Observable 3. Sets the initial value of bundled SBML species `t_d`."
      },
      {
        "name": "initial_unresolved_tumor_observable_4",
        "label": "Initial Unresolved Tumor Observable 4",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.initial_unresolved_tumor_observable_4",
        "description": "Initial Unresolved Tumor Observable 4. Sets the initial value of bundled SBML species `t_i`."
      }
    ],
    "outputs": [
      {
        "name": "unresolved_tumor_observable_1",
        "maps_to": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.unresolved_tumor_observable_1"
      },
      {
        "name": "unresolved_tumor_observable_2",
        "maps_to": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.unresolved_tumor_observable_2"
      },
      {
        "name": "unresolved_tumor_observable_3",
        "maps_to": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.unresolved_tumor_observable_3"
      },
      {
        "name": "unresolved_tumor_observable_4",
        "maps_to": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.unresolved_tumor_observable_4"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.species_labels"
      }
    ]
  },
  "title": "Draghi2019 - Parameter identification of a model for prostate cancer treated by intermittent therapy Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model",
      "alias": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model_state"
      ],
      "from": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model_summary"
      ],
      "from": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model_species_labels"
      ],
      "from": "immunology_sbml_draghi2019_parameter_identification_of_a_model_f_model1911100005_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This is a mathematical describing the interaction between the prostate adenocarcinoma tumor environment, the prostate specific antigen (PSA) produced by hormone-dependent and hormone-independent tumor. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}

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