Coulibaly2019 - Interleukin-15 Signaling in HIF-1a Regulation in Natural Killer Cells Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_unresolved_signaling_observable_1",
        "label": "Initial Unresolved Signaling Observable 1",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.initial_unresolved_signaling_observable_1",
        "description": "Initial Unresolved Signaling Observable 1. Sets the initial value of bundled SBML species `y1_IL_15`."
      },
      {
        "name": "initial_unresolved_signaling_observable_2",
        "label": "Initial Unresolved Signaling Observable 2",
        "units": "native source value",
        "default": 0.05,
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.initial_unresolved_signaling_observable_2",
        "description": "Initial Unresolved Signaling Observable 2. Sets the initial value of bundled SBML species `y4_HIF_1a`."
      },
      {
        "name": "initial_unresolved_signaling_observable_3",
        "label": "Initial Unresolved Signaling Observable 3",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.initial_unresolved_signaling_observable_3",
        "description": "Initial Unresolved Signaling Observable 3. Sets the initial value of bundled SBML species `y5_HIF_1b`."
      },
      {
        "name": "initial_unresolved_signaling_observable_4",
        "label": "Initial Unresolved Signaling Observable 4",
        "units": "native source value",
        "default": 0.05,
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.initial_unresolved_signaling_observable_4",
        "description": "Initial Unresolved Signaling Observable 4. Sets the initial value of bundled SBML species `y6_HIF_1_Complex`."
      },
      {
        "name": "initial_unresolved_signaling_observable_5",
        "label": "Initial Unresolved Signaling Observable 5",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.initial_unresolved_signaling_observable_5",
        "description": "Initial Unresolved Signaling Observable 5. Sets the initial value of bundled SBML species `y7_NF_KB`."
      }
    ],
    "outputs": [
      {
        "name": "unresolved_signaling_observable_1",
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.unresolved_signaling_observable_1"
      },
      {
        "name": "unresolved_signaling_observable_2",
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.unresolved_signaling_observable_2"
      },
      {
        "name": "unresolved_signaling_observable_3",
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.unresolved_signaling_observable_3"
      },
      {
        "name": "unresolved_signaling_observable_4",
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.unresolved_signaling_observable_4"
      },
      {
        "name": "unresolved_signaling_observable_5",
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.unresolved_signaling_observable_5"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.species_labels"
      }
    ]
  },
  "title": "Coulibaly2019 - Interleukin-15 Signaling in HIF-1a Regulation in Natural Killer Cells Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model",
      "alias": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model_state"
      ],
      "from": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model_summary"
      ],
      "from": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model_species_labels"
      ],
      "from": "immunology_sbml_coulibaly2019_interleukin_15_signaling_in_hif_1a_biomd0000000867_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This is a mathematical model comprised of non-linear ordinary differential equations describing the dynamic relationship between hypoxia-inducible factor-1 alpha (HIF-1a) mRNA, HIF-1a protein, and int. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}