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DeBoeck2021 - Modular approach to modeling the cell cycle, 5 ODE model with 3 bistable switches Lab

About lab

Single-model lab wrapper for DeBoeck2021 - Modular approach to modeling the cell cycle, 5 ODE model with 3 bistable switches. Model of the mammalian cell cycle as a chain of bistable switches. There are three bistable responses: response of E2F to Cyclin D, of Cdk1 to Cyclin B and of APC/C to Cdk1 activity.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagedeboeck2021-modular-approach-to-modeling-the-cell-cycle-5-ode-mo
Created2026-05-15
Updated2026-05-15
cellcyclesbmlbiomodels_ebifaithfulvisualisation

Manifest

{
  "io": {
    "inputs": [],
    "outputs": [
      {
        "name": "cyclin_d",
        "label": "Cyclin D",
        "maps_to": "cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model.cyclin_d",
        "description": "Tracks Cyclin D in the lab model via `cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model.cyclin_d`."
      },
      {
        "name": "cyclin_b",
        "label": "Cyclin B",
        "maps_to": "cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model.cyclin_b",
        "description": "Tracks Cyclin B in the lab model via `cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model.cyclin_b`."
      }
    ]
  },
  "title": "DeBoeck2021 - Modular approach to modeling the cell cycle, 5 ODE model with 3 bistable switches Lab",
  "models": [
    {
      "path": "owned/models/cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model",
      "alias": "cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model",
      "provenance": {
        "owned_path": "owned/models/cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model_state"
      ],
      "from": "cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model.state"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model_summary"
      ],
      "from": "cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model.summary"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model_species_labels"
      ],
      "from": "cellcycle_sbml_deboeck2021_modular_approach_to_modeling_the_cel_biomd0000001080_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "Single-model lab wrapper for DeBoeck2021 - Modular approach to modeling the cell cycle, 5 ODE model with 3 bistable switches. Model of the mammalian cell cycle as a chain of bistable switches. There are three bistable responses: response of E2F to Cyclin D, of Cdk1 to Cyclin B and of APC/C to Cdk1 activity.",
  "schema_version": "2.0"
}

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