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Baugh1998 Regulation Of Coagulation Factor Xa By Tfpi Lab

About lab

Basic mathematical model of the formation of coagulation factor Xa involving TF:VIIa and its inhibition by TFPI. It can be used to explore systemsbiology baugh1998 regulation of coagulation factor dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packagebaugh1998-regulation-of-coagulation-factor-xa-by-tfpi-lab
Created2026-05-17
Updated2026-05-17
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_model_state_p_i",
        "label": "Initial Model State P I",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.initial_model_state_p_i",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `P_I`."
      },
      {
        "name": "initial_ep_i",
        "label": "Initial Ep I",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.initial_ep_i",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `EP_I`."
      },
      {
        "name": "initial_model_state_es",
        "label": "Initial Model State Es",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.initial_model_state_es",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ES`."
      },
      {
        "name": "initial_model_state_s",
        "label": "Initial Model State S",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.initial_model_state_s",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `S`."
      },
      {
        "name": "initial_model_state_i",
        "label": "Initial Model State I",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.initial_model_state_i",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `I`."
      },
      {
        "name": "initial_model_state_e",
        "label": "Initial Model State E",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.initial_model_state_e",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `E`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.species_labels"
      },
      {
        "name": "p_i",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.p_i"
      },
      {
        "name": "ep_i",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.ep_i"
      },
      {
        "name": "model_state_es",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.model_state_es"
      },
      {
        "name": "model_state_s",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.model_state_s"
      },
      {
        "name": "model_state_i",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.model_state_i"
      },
      {
        "name": "model_state_e",
        "maps_to": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.model_state_e"
      }
    ]
  },
  "tags": [
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Baugh1998 Regulation Of Coagulation Factor Xa By Tfpi Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model",
      "alias": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model_state"
      ],
      "from": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model_summary"
      ],
      "from": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model_species_labels"
      ],
      "from": "systemsbiology_sbml_baugh1998_regulation_of_coagulation_factor_xa_by_model1807180001_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Basic mathematical model of the formation of coagulation factor Xa involving TF:VIIa and its inhibition by TFPI. It can be used to explore systemsbiology baugh1998 regulation of coagulation factor dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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