COVID-19 Immunotherapy 2021 Innate Immunity Model Lab

{
  "io": {
    "inputs": [
      {
        "name": "virus_clearance_rate",
        "label": "Virus Clearance Rate",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.virus_clearance_rate"
      },
      {
        "name": "virus_production_rate",
        "label": "Virus Production Rate",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.virus_production_rate"
      },
      {
        "name": "infected_cell_death_rate",
        "label": "Infected Cell Death Rate",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.infected_cell_death_rate"
      },
      {
        "name": "immune_activation_rate",
        "label": "Immune Activation Rate",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.immune_activation_rate"
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Model state",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Species labels",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.species_labels"
      },
      {
        "name": "treated_viral_load",
        "label": "Treated viral load",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.treated_viral_load"
      },
      {
        "name": "treated_free_virus",
        "label": "Treated free virus",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.treated_free_virus"
      },
      {
        "name": "treated_infected_epithelial_cells",
        "label": "Treated infected epithelial cells",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.treated_infected_epithelial_cells"
      },
      {
        "name": "treated_activated_neutrophils",
        "label": "Treated activated neutrophils",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.treated_activated_neutrophils"
      },
      {
        "name": "treated_interleukin_12",
        "label": "Treated interleukin 12",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.treated_interleukin_12"
      },
      {
        "name": "treated_antibody_response",
        "label": "Treated antibody response",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.treated_antibody_response"
      },
      {
        "name": "treated_b_cells",
        "label": "Treated B cells",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.treated_b_cells"
      },
      {
        "name": "treatment_inhibition_signal",
        "label": "Treatment inhibition signal",
        "maps_to": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.treatment_inhibition_signal"
      }
    ]
  },
  "title": "COVID-19 Immunotherapy 2021 Innate Immunity Model Lab",
  "models": [
    {
      "path": "owned/models/epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model",
      "alias": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model",
      "parameters": {
        "model_path": "data/MODEL2109130003.xml",
        "integration_step": 0.1
      },
      "provenance": {
        "owned_path": "owned/models/epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model_state"
      ],
      "from": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.state"
    },
    {
      "to": [
        "visualisation.epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model_summary"
      ],
      "from": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.summary"
    },
    {
      "to": [
        "visualisation.epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model_species_labels"
      ],
      "from": "epidemiology_sbml_covid_19_immunotherapy_a_mathematical_model_model2109130003_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Single-model lab wrapper for COVID-19 immunotherapy A mathematical model. We propose a within-host population (ODE) innate immunity model, whose focus is on NK cells and their relevant role in preventing COVID19 from progressing to the acute phase that may eventually lead t. It can be used to explore transmission dynamics and compare scenario outcomes across conditions.",
  "schema_version": "2.0"
}