Immunological Model Of Sphingolipids With Il 6 Il 17 Il 23 In L Major Infection Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_inflammatory_cytokine_genes",
        "label": "Initial Inflammatory Cytokine Genes",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.initial_inflammatory_cytokine_genes",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mw206507a8_49d3_4b89_8767_b96e224682c5`."
      },
      {
        "name": "initial_rorgt_gene",
        "label": "Initial Rorgt Gene",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.initial_rorgt_gene",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mw9d11e8ee_71f2_4317_9941_56b7d2e06360`."
      },
      {
        "name": "initial_il17_gene",
        "label": "Initial Il17 Gene",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.initial_il17_gene",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mw216e700c_7d7b_4257_979b_ce4f450c69eb`."
      },
      {
        "name": "initial_sphk_genes",
        "label": "Initial Sphk Genes",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.initial_sphk_genes",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mwb54ed2c0_8c56_445c_87dc_3297495bcb51`."
      },
      {
        "name": "initial_s1_pr_gene",
        "label": "Initial S1 Pr Gene",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.initial_s1_pr_gene",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mw5b840e2d_377b_422a_9e21_3233425a594b`."
      },
      {
        "name": "initial_inflammatory_cytokine_genes_2",
        "label": "Initial Inflammatory Cytokine Genes 2",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.initial_inflammatory_cytokine_genes_2",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `mwff98169b_8370_40b4_8ae6_91da20b7a11b`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.species_labels"
      },
      {
        "name": "inflammatory_cytokine_genes",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.inflammatory_cytokine_genes"
      },
      {
        "name": "rorgt_gene",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.rorgt_gene"
      },
      {
        "name": "il17_gene",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.il17_gene"
      },
      {
        "name": "sphk_genes",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.sphk_genes"
      },
      {
        "name": "s1_pr_gene",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.s1_pr_gene"
      },
      {
        "name": "inflammatory_cytokine_genes_2",
        "maps_to": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.inflammatory_cytokine_genes_2"
      }
    ]
  },
  "tags": [
    "epidemiology",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Immunological Model Of Sphingolipids With Il 6 Il 17 Il 23 In L Major Infection Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model_state"
      ],
      "from": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model_summary"
      ],
      "from": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model_species_labels"
      ],
      "from": "systemsbiology_sbml_immunological_model_of_sphingolipids_with_il_6_i_model2301110001_model.species_labels"
    }
  ],
  "package": "immunological-model-of-sphingolipids-with-il-6-il-17-il-5376bd93",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "In diseased state, we demonstrated that increase in production of sphingosine-1-phosphate and overexpression of IL-6,lL-17 and IL-23 with SATB1 leads to disease progression. It can be used to explore systemsbiology immunological of sphingolipids with il dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}